Results 281 to 290 of about 2,104,193 (346)

Cross‐Modal Denoising and Integration of Spatial Multi‐Omics Data with CANDIES

open access: yesAdvanced Science, EarlyView.
In this paper, we introduce CANDIES, which leverages a conditional diffusion model and contrastive learning to effectively denoise and integrate spatial multi‐omics data. We conduct extensive evaluations on diverse synthetic and real datasets, CANDIES shows superior performance on various downstream tasks, including denoising, spatial domain ...
Ye Liu   +5 more
wiley   +1 more source

Multi‐Omics Insights Into the Mechanisms of Early Muscle Fiber Difference and Transformation Between Lean‐Type and Chinese Indigenous Pigs

open access: yesAdvanced Science, EarlyView.
Multi‐omics analyses uncover breed‐specific cis‐regulatory landscapes and higher‐order chromatin architectural differences that underlie early postnatal muscle fiber divergence in pigs. A super‐enhancer upstream of PPP3CB recruits MEF2C to activate PPP3CB transcription, while the PPP3CB–MEF2C positive feedback loop promotes oxidative muscle fiber ...
Shuailong Zheng   +8 more
wiley   +1 more source

Estimation of genetic parameters for reproductive traits in Korean dairy cattle. [PDF]

open access: yesAnim Biosci
Lee JG   +7 more
europepmc   +1 more source

Transgenerational epigenetic heritability for growth, body composition, and reproductive traits in Landrace pigs. [PDF]

open access: yesFront Genet
Araujo AC   +6 more
europepmc   +1 more source

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