Results 131 to 140 of about 403,028 (282)

A Role for the Krebs Cycle Intermediate Citrate in Metabolic Reprogramming in Innate Immunity and Inflammation

open access: yesFrontiers in Immunology, 2018
Metabolism in immune cells is no longer thought of as merely a process for adenosine triphosphate (ATP) production, biosynthesis, and catabolism. The reprogramming of metabolic pathways upon activation is also for the production of metabolites that can ...
Niamh C. Williams, L. O’Neill
semanticscholar   +1 more source

Reprogramming the Histone Code

open access: yesChemistry & Biology, 2007
Histone lysine methyltransferases, like G9a, play central roles in the regulation of gene expression. A current study by Kubicek et al. [1] reports the identification of a G9a small-molecule inhibitor, thereby opening the way to new epigenetic cancer therapies.
Salam Shaaban, Mark T. Bedford
openaire   +3 more sources

Recent development on synthetic biological devices treating bladder cancer

open access: yesSynthetic and Systems Biotechnology, 2016
Synthetic biology is an emerging field focusing on engineering genetic devices and biomolecular systems for a variety of applications from basic biology to biotechnology and medicine.
Zhicong Chen   +4 more
doaj   +1 more source

Cellular reprogramming [PDF]

open access: yes, 2009
DNA-methylatie is een epigenetische modificatie. Dit type van modificaties verandert de genetische informatie zelf niet, maar wijzigt de laag erboven. Er worden chemische modificaties toegevoegd of gewijzigd op het DNA of de histonen (waarrond het DNA ...
Ongenaert, Maté
core   +1 more source

Correction: Up-regulation of long non-coding RNA PANDAR is associated with poor prognosis and promotes tumorigenesis in bladder cancer

open access: yesJournal of Experimental & Clinical Cancer Research, 2023
Yonghao Zhan   +13 more
doaj   +1 more source

Visualizing and analyzing global knowledge maps and emerging research trends in tumor-derived exosomes using CiteSpace

open access: yesDiscover Oncology
Objective Tumor-derived exosomes testing can be effective in diagnosing disease and assisting in the treatment of disease. Our study utilizes bibliometric analysis to identify research hotspots related to tumor-derived exosomes, predict emerging research
Ruijun Guo   +4 more
doaj   +1 more source

A systematic flux analysis approach to identify metabolic vulnerabilities in human breast cancer cell lines

open access: yesCancer & Metabolism, 2019
Background Increased flux through both glycolytic and oxidative metabolic pathways is a hallmark of breast cancer cells and is critical for their growth and survival.
Sheree D. Martin, Sean L. McGee
doaj   +1 more source

Direct cell reprogramming: approaches, mechanisms and progress

open access: yesNature reviews. Molecular cell biology, 2021
Haofei Wang   +3 more
semanticscholar   +1 more source

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