Results 41 to 50 of about 4,737,106 (385)

The anti‐CRISPR protein AcrIE8.1 inhibits the type I‐E CRISPR‐Cas system by directly binding to the Cascade subunit Cas11

open access: yesFEBS Letters, EarlyView.
In this study, we present the structure of AcrIE8.1, a previously uncharacterized anti‐CRISPR protein that inhibits the type I‐E CRISPR‐Cas system. Through a combination of structural and biochemical analyses, we demonstrate that AcrIE8.1 directly binds to the Cas11 subunit of the Cascade complex to inhibit the CRISPR‐Cas system.
Young Woo Kang, Hyun Ho Park
wiley   +1 more source

Czech Republic, Republic of Estonia, Hungary, Republic of Latvia, Republic of Lithuania, Republic of Poland, Slovak Republic, and Republic of Slovenia: Export Structure and Credit Growth

open access: yesIMF Staff Country Reports, 2006
Of the new members entering the European Union (EU) in May 2004, several had achieved a decade of impressive export growth, expanding significantly their shares of world markets. The empirical analysis shows that over the period 1994–2004, quality and technology upgrading associated with the structural transformation were, indeed, also associated with ...
openaire   +2 more sources

Understanding the illiberal turn: democratic backsliding in the Czech Republic*

open access: yesEast European Politics, 2018
Democratic backsliding in Central Europe has so far been most acute in Hungary and Poland, states once considered frontrunners in democratisation. In this paper, we explore to what extent developments in another key frontrunner, the Czech Republic, fit ...
S. Hanley, M. Vachudova
semanticscholar   +1 more source

Republic of Kazakhstan

open access: yesIMF Staff Country Reports, 2020
Selected ...
Léo-Paul Dana
semanticscholar   +1 more source

Cell density–dependent nuclear‐cytoplasmic shuttling of SETDB1 integrates with Hippo signaling to regulate YAP1‐mediated transcription

open access: yesFEBS Letters, EarlyView.
At low cell density, SETDB1 and YAP1 accumulate in the nucleus. As cell density increases, the Hippo pathway is gradually activated, and SETDB1 is associated with increased YAP1 phosphorylation. At high cell density, phosphorylated YAP1 is sequestered in the cytoplasm, while SETDB1 becomes polyubiquitinated and degraded by the ubiquitin–proteasome ...
Jaemin Eom   +3 more
wiley   +1 more source

The Second Republic of Europe

open access: yesEuropean Papers
(Series Information) European Papers - A Journal on Law and Integration, 2024 9(1), 461-462 | Editorial | (Abstract) Europe is changing its political genome. The ontologically political diversity between the Union and its Member States seems to wane. The
Enzo Cannizzaro
doaj   +1 more source

Doing Business in the Czech Republic [PDF]

open access: yes, 2012
[Excerpt] Baker & McKenzie is one of the world’s largest law firms with its presence in 70 locations in 42 countries. We have been active in the Czech Republic since 1993 and our work includes a full range of legal and tax services directed primarily to ...
Baker & McKenzie
core   +1 more source

Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology

open access: yesMolecular Oncology, EarlyView.
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts   +8 more
wiley   +1 more source

ACROSS TWO SEAS: COOPERATION AMONG SOCIAL SCIENCE SCHOLARS OF POLAND AND KAZAKHSTAN

open access: yesVestnik MGIMO-Universiteta, 2018
A collection of research papers by Polish, Kazakh and Lithuanian authors dedicated to the formation and development of modern Kazakhstan was published in 2016.
S. A. Sklyarov
doaj   +1 more source

The Structure of Consumer Basket in the Czech Republic and Slovak Republic [PDF]

open access: yes, 2014
Purpose of the article: Nowadays, consumer behaviour is still at the centre of attention of many researchers. The consumer basket belongs among important economic characteristics, which determine the economic level of each country.
Gottwald, Radim
core  

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