Results 51 to 60 of about 2,846,611 (292)
Networking in the Republic of Letters: Magliabechi and the Dutch Republic
Abstract The brokers who forge networks have exclusive access to diverse and innovative information. Hence, many histories of the Republic of Letters (1500–1800) stress the importance of brokers for the circulation and development of new ideas.
openaire +2 more sources
Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas +6 more
wiley +1 more source
A república kemalista na Turquia, 1923-1938
This essay examines the Ottoman debates about Republic in the nineteenth century and highlights the breathlessness of the monarchy between 1908 and 1922. It also analyzes the evolution of the Kemalist republic between 1923 and 1938.
Hamit Bozarslan
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Cinq ans après Charlie : Emmanuel Todd et le néorépublicanisme
As early as 2015, Emmanuel Todd published a book that offered an iconoclastic reading of "the spirit of January 11" that followed the attack on the editorial staff of the newspaper Charlie hebdo.
Alain Gabet
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The Anthropocene and the republic [PDF]
The Anthropocene, understood from the perspective of the creators of Earth System Science and IPCC, calls for global governance, which tends to be understood as an epistocratic, technocratic affair...
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Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee +7 more
wiley +1 more source
O sonho da República na Espanha do século XIX (1840-1868)
The first Republican groups have emerged in Spain in 1840. They had a growing popular support and a considerable weight in the historical dynamics of this period that led to the Revolution of 1868.
Florencia Peyrou, Manuel Pérez Ledesma
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Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
This paper explores, from a transnational perspective, the relation between war of independence and the construction of citizenship in territories belonging to Peru, Bolivia and the Northwest of Argentina.
Ana María Lorandi
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