Results 31 to 40 of about 3,204,256 (244)
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
FEBS Letters, EarlyView.EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
Liderança e localismo na I República brasileira
Ler História, 2010 Through an approach based on micro-analysis and focused on the study of individual paths, this essay is aimed to discuss issues related to the phenomenon of localism in the First Brazilian Republic (1889-1930).
Américo Freire
doaj +1 more source
Molecular Oncology, EarlyView.Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park +6 more
wiley +1 more source
European Papers(Series Information) European Papers - A Journal on Law and Integration, 2024 9(1), 461-462 | Editorial | (Abstract) Europe is changing its political genome. The ontologically political diversity between the Union and its Member States seems to wane. The
Enzo Cannizzaro
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O projecto educativo do republicanismo: o caso português numa perspectiva comparada
Ler História, 2010 Education was understood by Republicanism, like it happened in the French Third Republic, as a central element of the regeneration project of the Portuguese society.
Joaquim Pintassilgo
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Osmanlı’dan Cumhuriyet’e Modernleşme ve Müzik
Gaziantep Üniversitesi Sosyal Bilimler Dergisi, 2021 Sanat dalları arasında kendine has felsefi temeli, metodolojisi ve dili olan müzik, kendini var eden parametrelerle birlikte toplumla iç içe geçen bir yapıya sahip olmuştur.
Murat Özkul, Yunus Akif Çelikel
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Molecular Oncology, EarlyView.LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang +9 more
wiley +1 more source
A república kemalista na Turquia, 1923-1938
Ler História, 2010 This essay examines the Ottoman debates about Republic in the nineteenth century and highlights the breathlessness of the monarchy between 1908 and 1922. It also analyzes the evolution of the Kemalist republic between 1923 and 1938.
Hamit Bozarslan
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Molecular Oncology, EarlyView.This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic +10 more
wiley +1 more source
O sonho da República na Espanha do século XIX (1840-1868)
Ler História, 2010 The first Republican groups have emerged in Spain in 1840. They had a growing popular support and a considerable weight in the historical dynamics of this period that led to the Revolution of 1868.
Florencia Peyrou, Manuel Pérez Ledesma
doaj +1 more source