Results 61 to 70 of about 4,737,106 (385)

Perspectives in educating molecular pathologists on liquid biopsy: Toward integrative, equitable, and decentralized precision oncology

open access: yesMolecular Oncology, EarlyView.
Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié   +13 more
wiley   +1 more source

Church and State in Lithuania, Latvia and Estonia [PDF]

open access: yes, 1976
Glimpses of the Baltic ...
Moellering, Ralph L.
core   +1 more source

A comparative ethnobotany of Khevsureti, Samtskhe-Javakheti, Tusheti, Svaneti, and Racha-Lechkhumi, Republic of Georgia (Sakartvelo), Caucasus

open access: yesJournal of Ethnobiology and Ethnomedicine, 2016
BackgroundThe Republic of Georgia (Sakartvelo in Georgian language) is part of the Caucasus biodiversity hotspot, and human agricultural plant use dates bat at least 6000 years.
R. Bussmann   +8 more
semanticscholar   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

open access: yesMolecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla   +10 more
wiley   +1 more source

An Introduction to the Constitution of Polis through Religion(Politeia 327A-328B) [PDF]

open access: yesحکمت و فلسفه, 2012
As a rule, the introduction of scripts usually contains basic hints that through forthcoming lines will be explored and developed in more detail. The same is true about the introduction of Plato’s Politeia or Republic Book One.
mostafa younesi
doaj   +1 more source

Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin

open access: yesMolecular Oncology, EarlyView.
Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon   +4 more
wiley   +1 more source

GEOGRAFIA SIMBOLICĂ ŞI MONARHIA CONSTITUŢIONALĂ ÎN ROMÂNIA. SAU DE CE 1989 NU A FOST 1866 [PDF]

open access: yesRevista de Știinţe Politice şi Relaţii Internaţionale
The article presents and reevaluates the great and old Romanian political debate: republic vs. monarchy. Starting from the central value of the concept of strategic positioning in a „symbolic geography“, it argues that, by restoring the constitutional ...
Dungaciu, Dan
doaj  

Egaenus convexus - eine neue Weberknechtart aus der Tschechischen Republik [PDF]

open access: yes, 2013
The harvestmen fauna of the Czech Republic is relatively species-poor; so far 29 species have been found, of them 23 in Bohemia, the western part of the country, and 26 species in Moravia, the eastern part of the Czech ...
Bezdecka, Pavel, Klimes, Leos
core  

Indoleamine 2,3‐dioxygenase 1 inhibition reverses cancer‐associated fibroblast‐mediated immunosuppression in high‐grade serous ovarian cancer

open access: yesFEBS Open Bio, EarlyView.
CAF‐mediated immunosuppression in ovarian cancer is driven by IDO1, reducing T‐cell function. Inhibiting IDO1 restores T‐cell proliferation and cytotoxicity, increases cancer cell apoptosis, and may help overcome CAF‐induced immune suppression in high‐grade serous ovarian cancer. Targeting IDO1 may improve antitumor immunity.
Hyewon Lee   +3 more
wiley   +1 more source

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