Results 21 to 30 of about 139,836 (280)
Repurposing potential of ketamine: Opportunities and challenges
Indian Journal of Psychological Medicine, 2020 Ketamine is a noncompetitive antagonist of the N-methyl-D-aspartate (NMDA) receptor which also interacts with various other receptors that account for its myriad actions.
C S Gautam +4 more
doaj +1 more source
ImmPort, toward repurposing of open access immunological assay data for translational and clinical research [PDF]
, 2018 Immunology researchers are beginning to explore the possibilities of reproducibility, reuse and secondary analyses of immunology data. Open-access datasets are being applied in the validation of the methods used in the original studies, leveraging ...
Bhattacharya, Sanchita +12 more
core +2 more sources
Reinventing Therapeutic Proteins: Mining a Treasure of New Therapies
Biologics, 2023 Reinventing approved therapeutic proteins for a new dose, a new formulation, a new route of administration, an improved safety profile, a new indication, or a new conjugate with a drug or a radioactive source is a creative approach to benefit from the ...
Sarfaraz K. Niazi, Zamara Mariam
doaj +1 more source
A brief overview of current drug repurposing approaches for COVID-19 management [PDF]
, 2020 This brief overview is intended to shed light on the current drug repositioning (also called drug repurposing) in the therapeutics of the novel coronavirus disease which emerged in 2019 (COVID-19).
Rodrigues, Pedro da Fonseca Soares +1 more
core +2 more sources
Frontiers in Microbiology, 2022 Objectives:To evaluate the in vitro antibacterial, antibiofilm, and antivirulence activities of apramycin, comparatively to tobramycin, against a set of P.
Giovanni Di Bonaventura +12 more
doaj +1 more source
Drug Repositioning for Effective Prostate Cancer Treatment
Frontiers in Physiology, 2018 Drug repositioning has gained attention from both academia and pharmaceutical companies as an auxiliary process to conventional drug discovery. Chemotherapeutic agents have notorious adverse effects that drastically reduce the life quality of cancer ...
Beste Turanli +9 more
doaj +1 more source
, 2023 The book chapter explores repurposing as an innovation strategy for product development in various industries. While the general mindset around innovation is about creating something new, less emphasis has been placed on managing innovation and new product development based on new applications of existing solutions.
Hanisch, Marvin, Rake, Bastian
openaire +3 more sources
The Repurposing of Anti-Psychotic Drugs, Quetiapine and Olanzapine, as Anti-Cryptococcus Drugs
Frontiers in Microbiology, 2017 The management of cryptococcal infections is often difficult. This can, in part, be attributed to the fungistatic nature of fluconazole, which may result in cells disseminating to give rise to pathogen-emergent psychosis following brain inflammation ...
Adepemi O. Ogundeji +2 more
doaj +1 more source
Repurposing Therapeutics for Potential Treatment of SARS-CoV-2: A Review
Viruses, 2020 The need for proven disease-specific treatments for the novel pandemic coronavirus SARS-CoV-2 necessitates a worldwide search for therapeutic options. Since the SARS-CoV-2 virus shares extensive homology with SARS-CoV and MERS-CoV, effective therapies ...
Jennifer Santos +5 more
doaj +1 more source
Patient-specific data fusion for cancer stratification and personalised treatment [PDF]
, 2016 According to Cancer Research UK, cancer is a leading cause of death accounting for more than one in four of all deaths in 2011. The recent advances in experimental technologies in cancer research have resulted in the accumulation of large amounts of ...
Gligorijević, V +2 more
core +1 more source