Results 31 to 40 of about 142,289 (185)
Repurposing designed mutants: a valuable strategy for computer-aided laccase engineering – the case of POXA1b [PDF]
, 2017 The broad specificity of laccases, a direct consequence of their shallow binding site, makes this class of enzymes a suitable template to build specificity toward putative substrates.
Giacobelli, Valerio G. +6 more
core +2 more sources
Patient-specific data fusion for cancer stratification and personalised treatment [PDF]
, 2016 According to Cancer Research UK, cancer is a leading cause of death accounting for more than one in four of all deaths in 2011. The recent advances in experimental technologies in cancer research have resulted in the accumulation of large amounts of ...
Gligorijević, V +2 more
core +1 more source
Reuse remix recycle: repurposing archaeological digital data [PDF]
, 2018 Preservation of digital data is predicated on the expectation of its reuse, yet that expectation has never been examined within archaeology. While we have extensive digital archives equipped to share data, evidence of reuse seems paradoxically limited ...
Huggett, Jeremy
core +1 more source
Universa Medicina, 2023 Background Urinary tract infections are often initiated by indwelling catheters and bring about serious consequences, especially when they are caused by multidrug-resistant bacterial pathogens.
Muhammad Musthafa Poyil +2 more
doaj +1 more source
Understanding tissue morphology: model repurposing using the CoSMoS process [PDF]
, 2014 We present CoSMoS as a way of structuring thinking on how to reuse parts of an existing model and simulation in a new model and its implementation. CoSMoS provides a lens through which to consider, post-implementation, the assumptions made during the ...
Bown, James L. +4 more
core +3 more sources
Repurposing Pilocarpine Hydrochloride for Treatment of
mSphere, 2019 Acetylcholine modulates the virulence of Candida albicans and regulates an appropriate immune response to infection in a Galleria mellonella infection model. Indeed, the evidence suggests that C.
Christopher Nile +11 more
doaj +1 more source
A Churn for the Better: Localizing Censorship using Network-level Path Churn and Network Tomography [PDF]
, 2017 Recent years have seen the Internet become a key vehicle for citizens around the globe to express political opinions and organize protests. This fact has not gone unnoticed, with countries around the world repurposing network management tools (e.g., URL ...
Anonymous +8 more
core +3 more sources
Frontiers in Cellular and Infection Microbiology, 2021 Malaria, a disease caused by the protozoan parasites Plasmodium spp., is still causing serious problems in endemic regions in the world. Although the WHO recommends artemisinin combination therapies for the treatment of malaria patients, the emergence of
Takuro Endo +3 more
doaj +1 more source
Therapeutic status of hydroxychloroquine in COVID-19: A review
Journal of Anaesthesiology Clinical Pharmacology, 2020 Hydroxychloroquine (HCQ), a 4-aminoquinoline, is used worldwide mainly for its role in management of malaria and rheumatoid arthritis. In the present pandemic of coronavirus disease (COVID)-2019, the drug is being repurposed, based on its in vitro ...
Kirandeep Kaur +2 more
doaj +1 more source
Nucleotide analogues and mpox: Repurposing the repurposable
Antiviral ResearchWhile the COVID-19 crisis is still ongoing, a new public health threat has emerged with recent outbreaks of monkeypox (mpox) infections in Africa. Mass vaccination is not currently recommended by the World Health Organization (WHO), and antiviral treatments are yet to be specifically approved for mpox, although existing FDA-approved drugs (Tecovirimat,
Ashleigh Shannon, Bruno Canard
openaire +5 more sources