Results 51 to 60 of about 142,289 (185)
Active Targeted Nanoemulsions for Repurposing of Tegaserod in Alzheimer’s Disease Treatment
Pharmaceutics, 2021 Background and Purpose: The activation of 5-HT4 receptors with agonists has emerged as a valuable therapeutic strategy to treat Alzheimer’s disease (AD) by enhancing the nonamyloidogenic pathway.
Line Séguy +9 more
doaj +1 more source
Repurposing Second-Life EV Batteries to Advance Sustainable Development: A Comprehensive Review
BatteriesWhile lithium-ion batteries (LIBs) have pushed the progression of electric vehicles (EVs) as a viable commercial option, they introduce their own set of issues regarding sustainable development.
Muhammad Nadeem Akram, Walid Abdul-Kader
doaj +1 more source
The role of mentoring in facilitating the process of repurposing OER [PDF]
, 2010 This paper presents the initial data analysis of a research that is work in progress. It discusses the role of mentoring and peer support in facilitating the process of repurposing open educational resources (OER).
Okada, Alexandra, Santos, Andreia
core
In silico and in vitro drug screening identifies new therapeutic approaches for Ewing sarcoma. [PDF]
, 2016 The long-term overall survival of Ewing sarcoma (EWS) patients remains poor; less than 30% of patients with metastatic or recurrent disease survive despite aggressive combinations of chemotherapy, radiation and surgery.
Alturkmani, Hani +11 more
core +3 more sources
Microorganisms, 2023 There is a great need for novel approaches to treating bacterial infections, due to the vast dissemination of resistance among pathogenic bacteria.
Samar Zuhair Alshawwa +6 more
doaj +1 more source
Breaking the paradigm: Dr Insight empowers signature-free, enhanced drug repurposing [PDF]
, 2019 Motivation: Transcriptome-based computational drug repurposing has attracted considerable interest by bringing about faster and more cost-effective drug discovery.
Baldwin, Nicole E. +4 more
core +1 more source
Upscaling Lithium-ion Batteries for Small Scale Applications [PDF]
E3S Web of ConferencesElectricity is a necessity, and batteries are a common way to store and use energy. Different types of batteries such as lithium-ion are used in devices such as laptops and power banks. However, when the battery management system fails, the whole battery
Vanishree Sah P. +3 more
doaj +1 more source
Pharmaceuticals, 2023 The outbreak of the COVID-19 pandemic has spread throughout the world, affecting almost all nations and territories. The current double-blind, randomized, placebo-controlled, phase II clinical trial sought to evaluate the clinical efficacy and safety of ...
Mohamed El-Tanani +4 more
doaj +1 more source
Universal Broadband: Targeting Investments to Deliver Broadband Services to All Americans [PDF]
, 2010 Suggests ways to implement Knight's 2009 recommendation for universal broadband access, including repurposing and distributing existing funds via a transparent, market-based approach and supporting adoption by low-income and other non-adopter ...
Blair Levin
core
Repurposing the KCa3.1 inhibitor senicapoc for Alzheimer's disease. [PDF]
, 2019 ObjectiveMicroglia play a pivotal role in the initiation and progression of Alzheimer's disease (AD). We here tested the therapeutic hypothesis that the Ca2+-activated potassium channel KCa3.1 constitutes a potential target for treating AD by reducing ...
Bushong, Trevor +8 more
core +2 more sources