Results 61 to 70 of about 139,836 (280)
FEBS Open Bio, EarlyView.Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid +3 more
wiley +1 more source
Upscaling Lithium-ion Batteries for Small Scale Applications [PDF]
E3S Web of ConferencesElectricity is a necessity, and batteries are a common way to store and use energy. Different types of batteries such as lithium-ion are used in devices such as laptops and power banks. However, when the battery management system fails, the whole battery
Vanishree Sah P. +3 more
doaj +1 more source
Pharmaceuticals, 2023 The outbreak of the COVID-19 pandemic has spread throughout the world, affecting almost all nations and territories. The current double-blind, randomized, placebo-controlled, phase II clinical trial sought to evaluate the clinical efficacy and safety of ...
Mohamed El-Tanani +4 more
doaj +1 more source
Breaking the paradigm: Dr Insight empowers signature-free, enhanced drug repurposing [PDF]
, 2019 Motivation: Transcriptome-based computational drug repurposing has attracted considerable interest by bringing about faster and more cost-effective drug discovery.
Baldwin, Nicole E. +4 more
core +1 more source
Laser‐Induced Graphene from Waste Almond Shells
Advanced Functional Materials, EarlyView.Almond shells, an abundant agricultural by‐product, are repurposed to create a fully bioderived almond shell/chitosan composite (ASC) degradable in soil. ASC is converted into laser‐induced graphene (LIG) by laser scribing and proposed as a substrate for transient electronics.
Yulia Steksova +9 more
wiley +1 more source
Why the Hardship? Islam, Christianity, and Instrumental Affliction
Open Theology, 2020 Viewing hardship through the Western tradition of theodicy, Western theologians and philosophers sometimes approach their Muslim neighbors with questions about the Islamic perspective on suffering.
Pieper Christopher Nicolas
doaj +1 more source
Perhexiline: Old Drug, New Tricks? A Summary of Its Anti-Cancer Effects
Molecules, 2023 Cancer metabolic plasticity, including changes in fatty acid metabolism utilisation, is now widely appreciated as a key driver for cancer cell growth, survival and malignancy.
Bimala Dhakal +6 more
doaj +1 more source
Universal Broadband: Targeting Investments to Deliver Broadband Services to All Americans [PDF]
, 2010 Suggests ways to implement Knight's 2009 recommendation for universal broadband access, including repurposing and distributing existing funds via a transparent, market-based approach and supporting adoption by low-income and other non-adopter ...
Blair Levin
core
Advanced Functional Materials, EarlyView.A previously unreported coordination motif stabilising single Fe atoms by indigo chelation and pyridyl coordination on Au(111) has been revealed. By using planar tritopic pyridyl linkers (TPyB), extended 2D porous networks of indigo3(TPyB)2Fe6 form. These networks can be crystalline or vitreous and offer an environment where individual coordination ...
Hongxiang Xu +9 more
wiley +1 more source
COVID-19 at a Glance: An Up-to-Date Overview on Variants, Drug Design and Therapies
Viruses, 2022 Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) is a member of the Coronavirus family which caused the worldwide pandemic of human respiratory illness coronavirus disease 2019 (COVID-19).
Domenico Iacopetta +8 more
doaj +1 more source