Results 61 to 70 of about 142,289 (185)

Why the Hardship? Islam, Christianity, and Instrumental Affliction

Open Theology, 2020
Viewing hardship through the Western tradition of theodicy, Western theologians and philosophers sometimes approach their Muslim neighbors with questions about the Islamic perspective on suffering.
Pieper Christopher Nicolas
doaj   +1 more source

Perhexiline: Old Drug, New Tricks? A Summary of Its Anti-Cancer Effects

Molecules, 2023
Cancer metabolic plasticity, including changes in fatty acid metabolism utilisation, is now widely appreciated as a key driver for cancer cell growth, survival and malignancy.
Bimala Dhakal, Yoko Tomita, Paul Drew, Timothy Price, Guy Maddern, Eric Smith, Kevin Fenix   +6 more
doaj   +1 more source

Shuttered Public Schools: The Struggle to Bring Old Buildings New Life [PDF]

, 2013
Large-scale public school closures have become a fact of life in many American cities, and that trend is not likely to stop now. This report looks at what happens to the buildings themselves, studying the experiences of Philadelphia and 11 other cities ...
Emily Dowdall, Susan Warner
core  

Repurposing Didanosine as a Potential Treatment for COVID-19 Using Single-Cell RNA Sequencing Data

mSystems, 2020
As of today (7 April 2020), more than 81,000 people around the world have died from the coronavirus disease 19 (COVID-19) pandemic. There is no approved drug or vaccine for COVID-19, although more than 10 clinical trials have been launched to test ...
Fadhl M. Alakwaa
doaj   +1 more source

COVID-19 at a Glance: An Up-to-Date Overview on Variants, Drug Design and Therapies

Viruses, 2022
Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) is a member of the Coronavirus family which caused the worldwide pandemic of human respiratory illness coronavirus disease 2019 (COVID-19).
Domenico Iacopetta, Jessica Ceramella, Alessia Catalano, Carmela Saturnino, Michele Pellegrino, Annaluisa Mariconda, Pasquale Longo, Maria Stefania Sinicropi, Stefano Aquaro   +8 more
doaj   +1 more source

Using ICT to support public and private community memories: case studies and lessons learned [PDF]

, 2006
Information communication technologies (ICTs) enable the development of memories across a variety of communities. We identify a spectrum of deployment from private through to open public spaces.
Collins, T., Gaved, Mark, Heath, T., Mulholland, P., Zdrahal, Z.   +4 more
core  

Klotho pathways, myelination disorders, neurodegenerative diseases, and epigenetic drugs [PDF]

, 2020
In this review we outline a rationale for identifying neuroprotectants aimed at inducing endogenous Klotho activity and expression, which is epigenetic action, by definition. Such an approach should promote remyelination and/or stimulate myelin repair by
Chen, Xiaohong, Faller, Douglas V., Glavas, Ioannis P., Harpp, David N., Kanara, Iphigenia, Kodukula, Krishna, Mavrakis, Anastasios N., Moos, Walter H., Pernokas, Julie, Pernokas, Mark, Pinkert, Carl A., Powers, Whitney R., Sampani, Konstantina, Steliou, Kosta, Vavvas, Demetrios G., Zamboni, Robert J.   +15 more
core   +1 more source

The MAO‐B Inhibitor Selegiline Reduces the Viability of Different Prostate Cancer Cell Lines and Enhances the Effects of Anti‐Androgen and Cytostatic Agents

Pharmacology Research & Perspectives
The current treatments for advanced prostate adenocarcinoma (PAC) include the androgen receptor antagonist enzalutamide and docetaxel‐based chemotherapy.
Anita Steib, Krisztina Pohóczky, Norbert Tóth, Viktória Kormos, József Kun, Tamás Kálai, László Mangel, Péter Mátyus, Zsuzsanna Helyes   +8 more
doaj   +1 more source

Guidelines for structuring learning and teaching opportunities relevant to educators’ open educational resource (OER) engagement [PDF]

, 2015
Six guidelines for structuring learning and teaching opportunities relevant to educators’ open educational resource (OER) engagement are proposed in this document.
Hood, Nina, Littlejohn, Allison
core   +1 more source

Identification of Potential Drug Targets in Helicobacter pylori Using In Silico Subtractive Proteomics Approaches and Their Possible Inhibition through Drug Repurposing

Pathogens, 2020
The class 1 carcinogen, Helicobacter pylori, is one of the World Health Organization’s high priority pathogens for antimicrobial development. We used three subtractive proteomics approaches using protein pools retrieved from: chokepoint reactions in the ...
Kareem A. Ibrahim, Omneya M. Helmy, Mona T. Kashef, Tharwat R. Elkhamissy, Mohammed A. Ramadan   +4 more
doaj   +1 more source