Results 71 to 80 of about 139,836 (280)

Shuttered Public Schools: The Struggle to Bring Old Buildings New Life [PDF]

, 2013
Large-scale public school closures have become a fact of life in many American cities, and that trend is not likely to stop now. This report looks at what happens to the buildings themselves, studying the experiences of Philadelphia and 11 other cities ...
Emily Dowdall, Susan Warner
core  

Light‐Responsive Enzyme‐Loaded Nanoparticles for Tunable Adhesion and Mechanical Wound Contraction

Advanced Functional Materials, EarlyView.
This study presents a photoactivatable enzyme‐loaded mesoporous nanoparticle system (MPDA_PaTy) that enables light‐triggered tunable tissue adhesion and facilitates mechanical wound contraction. Controlled enzymatic crosslinking at tissue or hydrogel interfaces allows on‐demand adhesion.
Junghyeon Ko, Hyeon‐Jin Kim, Jeong‐Uk Kim, Seh Ri Oh, Tae Hoon Kang, Junghwan Byun, Uk‐Jae Lee, Minglin Ma, Su‐Hwan Kim, Byung‐Gee Kim, Nathaniel S. Hwang   +10 more
wiley   +1 more source

Repurposing Didanosine as a Potential Treatment for COVID-19 Using Single-Cell RNA Sequencing Data

mSystems, 2020
As of today (7 April 2020), more than 81,000 people around the world have died from the coronavirus disease 19 (COVID-19) pandemic. There is no approved drug or vaccine for COVID-19, although more than 10 clinical trials have been launched to test ...
Fadhl M. Alakwaa
doaj   +1 more source

Mefloquine, a Potent Anti-severe Acute Respiratory Syndrome-Related Coronavirus 2 (SARS-CoV-2) Drug as an Entry Inhibitor in vitro

Frontiers in Microbiology, 2021
Coronavirus disease 2019 (COVID-19) has caused serious public health, social, and economic damage worldwide and effective drugs that prevent or cure COVID-19 are urgently needed.
Kaho Shionoya, Kaho Shionoya, Masako Yamasaki, Masako Yamasaki, Shoya Iwanami, Shoya Iwanami, Yusuke Ito, Shuetsu Fukushi, Hirofumi Ohashi, Hirofumi Ohashi, Wakana Saso, Wakana Saso, Wakana Saso, Tomohiro Tanaka, Shin Aoki, Kouji Kuramochi, Shingo Iwami, Shingo Iwami, Shingo Iwami, Shingo Iwami, Shingo Iwami, Shingo Iwami, Shingo Iwami, Yoshimasa Takahashi, Yoshimasa Takahashi, Tadaki Suzuki, Masamichi Muramatsu, Makoto Takeda, Takaji Wakita, Koichi Watashi, Koichi Watashi, Koichi Watashi, Koichi Watashi, Koichi Watashi   +33 more
doaj   +1 more source

Music Information Retrieval in Live Coding: A Theoretical Framework [PDF]

, 2018
The work presented in this article has been partly conducted while the first author was at Georgia Tech from 2015–2017 with the support of the School of Music, the Center for Music Technology and Women in Music Tech at Georgia Tech. Another part of this
Freeman, Jason, Lerch, Alexander, Xambo, Anna   +2 more
core   +2 more sources

From Waste to Value: Conversion of Calcium Sulfate to Vaterite via Carbon Capture and Storage

Advanced Functional Materials, EarlyView.
This study introduces a new concept for carbon management that relies on the carbonation of industrial gypsum waste and yields phase‐pure vaterite at ambient conditions without any additives. The obtained vaterite is further shown to be a reactive material that develops compressive strength in aqueous suspensions like conventional cements.
Carlos Pimentel, German Montes‐Hernández, Pablo Almarza‐Cifuentes, Matthias Kellermeier, Alexander E.S. Van Driessche   +4 more
wiley   +1 more source

The MAO‐B Inhibitor Selegiline Reduces the Viability of Different Prostate Cancer Cell Lines and Enhances the Effects of Anti‐Androgen and Cytostatic Agents

Pharmacology Research & Perspectives
The current treatments for advanced prostate adenocarcinoma (PAC) include the androgen receptor antagonist enzalutamide and docetaxel‐based chemotherapy.
Anita Steib, Krisztina Pohóczky, Norbert Tóth, Viktória Kormos, József Kun, Tamás Kálai, László Mangel, Péter Mátyus, Zsuzsanna Helyes   +8 more
doaj   +1 more source

Using ICT to support public and private community memories: case studies and lessons learned [PDF]

, 2006
Information communication technologies (ICTs) enable the development of memories across a variety of communities. We identify a spectrum of deployment from private through to open public spaces.
Collins, T., Gaved, Mark, Heath, T., Mulholland, P., Zdrahal, Z.   +4 more
core  

Targeting ROCK activity to disrupt and prime pancreatic cancer for chemotherapy [PDF]

, 2017
Pancreatic ductal adenocarcinoma (PDAC) is a devastating disease; the identification of novel targets and development of effective treatment strategies are urgently needed to improve patient outcomes.
Olson, Michael F., Pajic, Marina, Rath, Nicola, Timpson, Paul, Vennin, Claire   +4 more
core   +1 more source

Klotho pathways, myelination disorders, neurodegenerative diseases, and epigenetic drugs [PDF]

, 2020
In this review we outline a rationale for identifying neuroprotectants aimed at inducing endogenous Klotho activity and expression, which is epigenetic action, by definition. Such an approach should promote remyelination and/or stimulate myelin repair by
Chen, Xiaohong, Faller, Douglas V., Glavas, Ioannis P., Harpp, David N., Kanara, Iphigenia, Kodukula, Krishna, Mavrakis, Anastasios N., Moos, Walter H., Pernokas, Julie, Pernokas, Mark, Pinkert, Carl A., Powers, Whitney R., Sampani, Konstantina, Steliou, Kosta, Vavvas, Demetrios G., Zamboni, Robert J.   +15 more
core   +1 more source