Results 81 to 90 of about 142,289 (185)
Repurposing metformin for cancer treatment: current clinical studies. [PDF]
In recent years, several studies have presented evidence suggesting a potential role for metformin in anti-cancer therapy. Preclinical studies have demonstrated several anticancer molecular mechanisms of metformin including mTOR inhibition, cytotoxic ...
Altman, Jessica K +10 more
core +1 more source
Targeting ROCK activity to disrupt and prime pancreatic cancer for chemotherapy [PDF]
Pancreatic ductal adenocarcinoma (PDAC) is a devastating disease; the identification of novel targets and development of effective treatment strategies are urgently needed to improve patient outcomes.
Olson, Michael F. +4 more
core +1 more source
UBC4: A Repurposed Drug Regimen for Adjunctive Use During Bladder Cancer Treatment
After it has metastasized, bladder cancer, the malignant transformation of the bladder urothelium, continues to be a common cause of death after maximal use of all currently available standard treatments.
Richard E. Kast
doaj +1 more source
Open Source Repurposing Reveals Broad-Spectrum Antiviral Activity of Diphenylureas
The pandemic threat from newly emerging viral diseases constitutes a major unsolved issue for global health. Antiviral therapy can play an important role in treating and preventing the spread of unprecedented viral infections.
Ulrich A. K. Betz +15 more
doaj +1 more source
Impact of knowledge management processes on organisational performance: A preliminary study [PDF]
Copyright @ 2013 EMCIS.Despite the increasing number of studies relating to Knowledge Management (KM) in developed countries, few studies have explored this issue within the context of developing countries.
Alalwany, H, Alshawi, SN, Tubigi, M
core
Cervical cancer presents a significant challenge to the global health of women. Despite substantial advances in human papillomavirus (HPV)-related cervical cancer vaccines, non-HPV-related cervical cancer is still waiting novel therapeutic options.
Zsuzsanna Schelz +4 more
doaj +1 more source
How Can Network-Pharmacology Contribute to Antiepileptic Drug Development? [PDF]
Network-pharmacology is a field of pharmacology emerging from the observation that most clinical drugs have multiple targets, contrasting with the previously dominant magic bullet paradigm which proposed the search of exquisitely selective drugs. What is
Di Ianni, Mauricio Emiliano +1 more
core +1 more source
The impact of knowledge management processes on organisational performance [PDF]
Copyright @ 2012 ISEing.In today's increasingly competitive business environment, the use of knowledge to gain a competitive advantage has become a serious concern for all organisations.
Alshawi, SN, Tubigi, MA
core
Composing For Public Audiences [PDF]
Project 3: Students were asked to identify a piece of scholarly research or prior inquiry they would like to share with a broader audience, by shifting it into a new modality, and framing its importance rhetorically for their target ...
Newmann Holmes, Alba
core +1 more source

