Results 151 to 160 of about 4,832,102 (292)

Color outside the lines: How does amoral management influence employees' creative unethicality? [PDF]

PLoS One
Ren L, Liu Y, Siyal AW, Zhang X, Pu T.
europepmc   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

FEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel, Carl P. O. Helmer, Shani Zev, Ronja Driller, Emily Buhr, Markus Reinbold, Renana Schwartz, Gabriel Foley, Mikael Boden, Daniel Garbe, Gerhard Schenk, Dan Thomas Major, Bernhard Loll, Thomas Brück   +13 more
wiley   +1 more source

Age-related reduction in ciprofol requirement for loss of consciousness during anesthesia induction: a prospective cohort study. [PDF]

Front Med (Lausanne)
Lu YG, Zhang FQ, He YY, Ding T, Deng F, Liu W, Song JC.   +6 more
europepmc   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

A transfer learning approach for automatic conflicts detection in software requirement sentence pairs based on dual encoders. [PDF]

PLoS One
Wang Y, Jiang T, Bai J, Zou Z, Xue T, Zhang N, Luan J.   +6 more
europepmc   +1 more source

Nutrition, more than body requirement: Risk [PDF]

, 1992
Frenn, Marilyn
core   +1 more source

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Ranchers' Preferences for Grazing Programs in the Voluntary Carbon Market: Insights from a Discrete Choice Experiment in the Great Plains and Front Range, USA. [PDF]

Environ Manage
Nimlos N, Bastian C, Scasta JD.
europepmc   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

Provenance-Specific Chilling and Forcing Requirements Shape Spring Phenology in Three European Temperate Tree Species. [PDF]

Glob Chang Biol
Wu Z, Walde MG, Beil I, Klisz M, Vitasse Y.   +4 more
europepmc   +1 more source