Results 51 to 60 of about 55,074 (196)
Effect of different digestible isoleucine/lysine ratios for broiler chickens
Revista Brasileira de Zootecnia, 2012 Two experiments were conducted to evaluate different digestible isoleucine/lysine ratios on diets for broiler chickens in the starter (7 to 21 days) and finishing (30 to 43 days) phases.
Fernando de Castro Tavernari +7 more
doaj +1 more source
FEBS Letters, EarlyView.This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley +1 more source
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
FEBS Letters, EarlyView.Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
Developing a continuous adjustment factor for dry matter intake of gestating and lactating ewes
Scientia Agricola, 2020 : Intake is a multifactorial process that is influenced by animal type, environmental factors, and diet characteristics. Sheep, especially, have specific eating habits, with a greater selection of ingested feed compared to cattle.
Sarita Bonagurio Gallo +1 more
doaj +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Integration of circadian and hypoxia signaling via non‐canonical heterodimerization
FEBS Letters, EarlyView.CLOCK, BMAL1, and HIFs are basic helix‐loop‐helix and Per‐Arnt‐Sim domain (bHLH‐PAS) proteins, which function as transcription factors. bHLH‐PAS proteins are designated in two classes. Many class I proteins are regulated by environmental signals via their PAS domains, but such signals have not been identified for all.
Sicong Wang, Katja A. Lamia
wiley +1 more source
Veterinary Medicine and ScienceBackground The vegetable‐based diet alone does not provide the lysine (Lys) needed to maximize poultry productive performance. Objectives This experiment aimed to evaluate the effects of dietary digestible Lys (dLys) level on productive and reproductive ...
Mohammad Amin Omary +2 more
doaj +1 more source
Iraqi Journal of Hematology, 2019 BACKGROUND: Acute leukemia is considered one of the most diseases that required frequent blood transfusion. Despite that blood transfusion is one of the main parts in the supportive management of acute leukemia patients, still, there are few data showing
Alaa Fadhil Alwan +2 more
doaj +1 more source
Function‐driven design of a surrogate interleukin‐2 receptor ligand
FEBS Letters, EarlyView.Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source