Results 101 to 110 of about 249,173 (312)

An approach for model based requirement engineering of participative engineering methodology

, 2007
In the context of the MAPPER project, the paper presents an approach for model based methodology requirement engineering with the mission of supporting the creation and utilisation of a requirement and assessment model enabling a dynamic representation ...
Johnsen, S. G., Rolfsen, R. K., Tellioglu, Hilda   +2 more
core   +1 more source

Requirement Engineering in Startups

Proceedings of the 16th International Conference on Software Technologies, 2021
Shatadru Shikta, Sowvik Kanti Das, Somania Nur Mahal, H. M. Mahir Shahriyar, Kazi Bushra Al Jannat, Mahady Hasan   +5 more
openaire   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source

Model-Based Systems Engineering for Digital Twin System Development Applied to an Aircraft Seat Test Bench

IEEE Access
In recent years, the Digital Twin has attracted significant attention in academia and industry as a powerful technology for creating virtual replicas of physical systems tailored to specific purposes.
Agnese Pasquariello, Imane Bouhali, Dominik Leherbauer, Nourhene Abdeljabbar, Faida Mhenni, Stanislao Patalano, Peter Hehenberger, Andrea Rega   +7 more
doaj   +1 more source

A Requirement Engineering Framework for Electric Motors Development

Applied Sciences, 2018
The applications using electric motors have increased in the last decade. Some of these applications encounter the need for tailor-made motors that must meet demanding requirements.
Christian A. Rivera, Javier Poza, Gaizka Ugalde, Gaizka Almandoz   +3 more
doaj   +1 more source

Software Engineering: Factors Affect on Requirement Prioritization

, 2012
Software engineering research is yet in its early stages hence it needs evaluation. So, software engineers think about experimental research and try to adopt analytical approaches to validate results like in other sciences.
Dr. Shams Ul Hassan, Salman Afsar Awan
core  

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

FEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas, Brigitta Maruzs, Zsófia E. Kálmán, Tomas Klumpler, Gyula Batta, Bálint Péterfia, Zoltán Gáspári   +6 more
wiley   +1 more source

Formal Modeling and Analysis Method for Hierarchical Requirements of Airborne Software

Nanjing Hangkong Hangtian Daxue Xuebao
The increasingly complex multi-level functional requirements bring challenges to the design and development of safety-critical airborne software. A formal modeling and analysis method of software requirements with hierarchical semantic characteristics ...
WANG Kangxing, HU Jun, WANG Lisong, DING Ding, DONG Yajiong, DAI Jialei   +5 more
doaj   +1 more source

Timing requirement description diagrams for real-time system verification [PDF]

, 2008
TURTLE is a real-time UML profile introduced a few years ago to address the analysis, design and deployment of time-constrained systems. The profile has a formal semantics. Further, it is supported by an open source toolkit: TTool.
Fontan, B, Apvrille, L., Saqui-Sannes, Pierre de, De Saqui-Sannes, P, Apvrille, Ludovic, Fontan, Benjamin   +5 more
core  

The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome

FEBS Letters, EarlyView.
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley   +1 more source