Results 91 to 100 of about 1,519,620 (289)

Scenario driven requirement engineering for design and deployment of mobile communication networks [PDF]

The numbers of users and usage of mobile data service are increasing dramatically due to the introduction of smartphones and mobile broadband dongles. For the next decade the mobile broadband market is expected to grow and reach a level where the average
Beckman, Claes, Markendahl, Jan, Mäkitalo, Östen, Mölleryd, Bengt G.   +3 more
core  

Towards a method for rigorous development of generic requirements patterns

, 2006
We present work in progress on a method for the engineering, validation and verification of generic requirements using domain engineering and formal methods. The need to develop a generic requirement set for subsequent system instantiation is complicated
A. Węsowski, B. Dehbonei, C. Snook, C. Snook, C.M. Belcastro, D. Batory, D. Muthig, G. Booch, J.-R. Abrial, L. Laibinis, L. Laibinis, M. Fayad, P. Amey, R. Banach, S.R. Faulk, W. Lam   +15 more
core   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

FEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel, Carl P. O. Helmer, Shani Zev, Ronja Driller, Emily Buhr, Markus Reinbold, Renana Schwartz, Gabriel Foley, Mikael Boden, Daniel Garbe, Gerhard Schenk, Dan Thomas Major, Bernhard Loll, Thomas Brück   +13 more
wiley   +1 more source

Optimizing Requirements Prioritization for IoT Applications Using Extended Analytical Hierarchical Process and an Advanced Grouping Framework

Future Internet
Effective requirement collection and prioritization are paramount within the inherently distributed nature of the Internet of Things (IoT) application.
Sarah Kaleem, Muhammad Asim, Mohammed El-Affendi, Muhammad Babar   +3 more
doaj   +1 more source

VISUALISASI DAN DOKUMENTASI METODE LWBA SECARA OTOMATIS DAN KONSISTEN UNTUK REQUIREMENT ENGINEERING [PDF]

, 2013
Visualisasi dalam requirement engineering dibutuhkan agar penyebab permasalahan menjadi lebih terjajaki (traceable). Di samping visualisasi, dibutuhkan juga deskripsi dari visualisasi.
Chandra, Reza, Wiryana, I Made
core  

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

BORM - overview of the methodology and case study of the agrarian information system

Agricultural Economics (AGRICECON), 2003
BORM (Business Object Relationship Modelling) is a methodology developed to capture the knowledge of process-based business systems. It has been in development since 1993 and has proved an effective method, which is popular with both users and analysts ...
V. Merunka
doaj   +1 more source