Results 81 to 90 of about 1,519,620 (289)

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source

Chromaticity in all-reflective telescopes for astrometry

, 2005
Chromatic effects are usually associated with refractive optics, so reflective telescopes are assumed to be free from them. We show that all-reflective optics still bears significant levels of such perturbations, which is especially critical to modern ...
D. Busonero, D. Gardiol, D. Loreggia, Gai, Gardiol, Gouda, Johnston, M. G. Lattanzi, M. Gai, Perryman   +9 more
core   +3 more sources

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Data management in balance – a decade of balancing pragmatism, sustainability and innovation at plant research center IPK Gatersleben

Journal of Integrative Bioinformatics
The Leibniz Institute of Plant Genetics and Crop Plant Research (IPK) Gatersleben is a leading international plant science institute specializing in biodiversity and crop plant performance research.
Schüler Danuta, Lange Matthias, Altmann Thomas, Cuacos Maria, Arend Daniel, D’Auria John Charles, Fiebig Anne, Kumlehn Jochen, Neumann Kerstin, Melzer Michael, Rey-Mazón Elena, Rolletschek Hardy, Scholz Uwe, Willner Evelin, Reif Jochen C.   +14 more
doaj   +1 more source

The use of the concept of event in enterprise ontologies and requirements engineering literature. [PDF]

The concept of event is used in a lot of meanings. It can be the possible outcome of doing something (probability theory), it can be a business transaction (accounting), or just a plain happening.
De Backer, Manu, Hens, Pieter, Poels, Geert, Snoeck, Monique   +3 more
core  

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

A systematic mapping to investigate the application of machine learning techniques in requirement engineering activities

CAAI Transactions on Intelligence Technology
Over the past few years, the application and usage of Machine Learning (ML) techniques have increased exponentially due to continuously increasing the size of data and computing capacity.
Shoaib Hassan, Qianmu Li, Khursheed Aurangzeb, Affan Yasin, Javed Ali Khan, Muhammad Shahid Anwar   +5 more
doaj   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

FEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto, Yukio Matsuba, Mika Takahashi, Takaomi C. Saido   +3 more
wiley   +1 more source

An Efficient Identification of Security Threats in Requirement Engineering Methodology. [PDF]

Comput Intell Neurosci, 2022
Subha R, Haldorai A.
europepmc   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source