Results 61 to 70 of about 217,174 (266)

Dynamic Reliability Analysis of Multi-component Structures Based on Moving Extremum Response Surface Method-based Decomposed Coordinative Strategy

Hangkong gongcheng jinzhan, 2020
The reliability analysis of complex structures assembled from multiple components has the problems of complicated calculation process and low calculation efficiency.
MA Nan, LU Cheng
doaj   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Data management in balance – a decade of balancing pragmatism, sustainability and innovation at plant research center IPK Gatersleben

Journal of Integrative Bioinformatics
The Leibniz Institute of Plant Genetics and Crop Plant Research (IPK) Gatersleben is a leading international plant science institute specializing in biodiversity and crop plant performance research.
Schüler Danuta, Lange Matthias, Altmann Thomas, Cuacos Maria, Arend Daniel, D’Auria John Charles, Fiebig Anne, Kumlehn Jochen, Neumann Kerstin, Melzer Michael, Rey-Mazón Elena, Rolletschek Hardy, Scholz Uwe, Willner Evelin, Reif Jochen C.   +14 more
doaj   +1 more source

BORM - overview of the methodology and case study of the agrarian information system

Agricultural Economics (AGRICECON), 2003
BORM (Business Object Relationship Modelling) is a methodology developed to capture the knowledge of process-based business systems. It has been in development since 1993 and has proved an effective method, which is popular with both users and analysts ...
V. Merunka
doaj   +1 more source

A Study of Emotions in Requirements Engineering [PDF]

, 2010
Requirements engineering (RE) is a crucial activity in software development projects. This phase in the software development cycle is knowledge intensive, and thus, human capital intensive. From the human point of view, emotions play an important role in behavior and can even act as behavioral motivators.
Ricardo Colomo-Palacios, Adrián Hernández-López, Ángel García-Crespo, Pedro Soto-Acosta   +3 more
openaire   +2 more sources

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

A systematic mapping to investigate the application of machine learning techniques in requirement engineering activities

CAAI Transactions on Intelligence Technology
Over the past few years, the application and usage of Machine Learning (ML) techniques have increased exponentially due to continuously increasing the size of data and computing capacity.
Shoaib Hassan, Qianmu Li, Khursheed Aurangzeb, Affan Yasin, Javed Ali Khan, Muhammad Shahid Anwar   +5 more
doaj   +1 more source

An Efficient Identification of Security Threats in Requirement Engineering Methodology. [PDF]

Comput Intell Neurosci, 2022
Subha R, Haldorai A.
europepmc   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

FEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa, Akira Hattori, Masafumi Tsujimoto, Toshihide Kobayashi   +3 more
wiley   +1 more source