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ABSTRACT Background Neuromyelitis optica spectrum disorder (NMOSD) is a relapsing autoimmune disease of the central nervous system. High‐dose intravenous methylprednisolone (IVMP) is the standard first‐line therapy for acute attacks, although some patients remain refractory.
Wataru Horiguchi +5 more
wiley +1 more source
Software requirement artifacts such as manuals request for proposals, and software requirements specification (SRS) are commonly focused on functional requirements.
Muhammad Asif +5 more
doaj +1 more source
Requirements engineering is the initial phase of the software development life cycle it is a critical aspect of application development since it has a significant impact on the results of the product being created. This article focuses on the engineering
Dwi Hosanna Bangkalang +4 more
doaj +1 more source
Pengembangan Tools pada Fase Requirement Engineering dengan Metode LWBA [PDF]
Pendeskripsian pada fase requirement engineering dibutuhkan agar penyebab permasalahan menjadi lebih terjajaki (traceable). Yang menjadi permasalahan dari dokumentasi pada fase requirement engineering adalah seringkali timbul inkonsistensi dalam ...
Chandra, Reza
core
Understanding Social and Environmental Requirements in China [PDF]
Rapid changes in the social and technical environment bring about many new challenges to system requirements engineering, amongst which out-sourcing or off-shoring of certain design tasks to countries with more human resources and broader markets becomes
Liu, Lin
core +1 more source
Organoids in pediatric cancer research
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
FRUIT: Fuzzy Representation of Unbounded and Imprecise Terms in Non-Functional Requirements
It is challenging to verify Non-Functional Requirements (NFRs) because the traditional verification process typically uses the binary concept of true or false to determine whether a requirement has been fulfilled, leaving no space for uncertainty, even ...
Franklin Parrales-Bravo +3 more
doaj +1 more source
ESTABLISHING REQUIREMENT IN TEACHING NEW AND RENEWABLE ENERGY
The distinctive shortage in the availability of skilled labor in new and renewable energy sector becomes the issue that has been prevented this country in achieving the national energy mix in 2015 and 2050.
Meredita Susanty +2 more
doaj +1 more source
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source

