Results 61 to 70 of about 1,511,705 (293)
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Quantum control in infinite dimensions
Accurate control of quantum evolution is an essential requirement for quantum state engineering, laser chemistry, quantum information and quantum computing.
Ball +7 more
core +2 more sources
Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang +8 more
wiley +1 more source
Requirements engineering is the initial phase of the software development life cycle it is a critical aspect of application development since it has a significant impact on the results of the product being created. This article focuses on the engineering
Dwi Hosanna Bangkalang +4 more
doaj +1 more source
Requirement engineering of a Cooperative Information System using viewpoints [PDF]
International audienceIn this paper we are interested in cooperative infor-mation systems (CIS) in inter-organizational environments. They are information systems on a large scale, which con-nect different organizations, often autonomous, sharing common ...
Alimazighi, Zaia +2 more
core +2 more sources
Quantum detector tomography is a fundamental technique for calibrating quantum devices and performing quantum engineering tasks. In this paper, a novel quantum detector tomography method is proposed.
Dong, Daoyi +5 more
core +2 more sources
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
FRUIT: Fuzzy Representation of Unbounded and Imprecise Terms in Non-Functional Requirements
It is challenging to verify Non-Functional Requirements (NFRs) because the traditional verification process typically uses the binary concept of true or false to determine whether a requirement has been fulfilled, leaving no space for uncertainty, even ...
Franklin Parrales-Bravo +3 more
doaj +1 more source
Engineers for the future; accounting for diversity [PDF]
tailoring engineering and STEM education to meet the needs of all stakeholders. (External Industry requirement) a. Educational institutions must consider an increasingly diverse group of stakeholders, including students, staff, industry, and the wider ...
AL-Rawi, Mohammad
core
Hierarchical Gaussian process mixtures for regression [PDF]
As a result of their good performance in practice and their desirable analytical properties, Gaussian process regression models are becoming increasingly of interest in statistics, engineering and other fields.
A. Gelman +17 more
core +3 more sources

