Results 61 to 70 of about 1,511,705 (293)

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

Quantum control in infinite dimensions

open access: yes, 2003
Accurate control of quantum evolution is an essential requirement for quantum state engineering, laser chemistry, quantum information and quantum computing.
Ball   +7 more
core   +2 more sources

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

open access: yesFEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang   +8 more
wiley   +1 more source

A REQUIREMENT ENGINEERING IN REPORTING AND COUNSELING-BASED ASSISTANCE APPLICATION FOR VICTIMS OF VIOLENCE AGAINST WOMEN

open access: yesJurnal Riset Informatika, 2021
Requirements engineering is the initial phase of the software development life cycle it is a critical aspect of application development since it has a significant impact on the results of the product being created. This article focuses on the engineering
Dwi Hosanna Bangkalang   +4 more
doaj   +1 more source

Requirement engineering of a Cooperative Information System using viewpoints [PDF]

open access: yes, 2014
International audienceIn this paper we are interested in cooperative infor-mation systems (CIS) in inter-organizational environments. They are information systems on a large scale, which con-nect different organizations, often autonomous, sharing common ...
Alimazighi, Zaia   +2 more
core   +2 more sources

Two-stage Estimation for Quantum Detector Tomography: Error Analysis, Numerical and Experimental Results

open access: yes, 2021
Quantum detector tomography is a fundamental technique for calibrating quantum devices and performing quantum engineering tasks. In this paper, a novel quantum detector tomography method is proposed.
Dong, Daoyi   +5 more
core   +2 more sources

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

FRUIT: Fuzzy Representation of Unbounded and Imprecise Terms in Non-Functional Requirements

open access: yesIEEE Access
It is challenging to verify Non-Functional Requirements (NFRs) because the traditional verification process typically uses the binary concept of true or false to determine whether a requirement has been fulfilled, leaving no space for uncertainty, even ...
Franklin Parrales-Bravo   +3 more
doaj   +1 more source

Engineers for the future; accounting for diversity [PDF]

open access: yes, 2018
tailoring engineering and STEM education to meet the needs of all stakeholders. (External Industry requirement) a. Educational institutions must consider an increasingly diverse group of stakeholders, including students, staff, industry, and the wider ...
AL-Rawi, Mohammad
core  

Hierarchical Gaussian process mixtures for regression [PDF]

open access: yes, 2004
As a result of their good performance in practice and their desirable analytical properties, Gaussian process regression models are becoming increasingly of interest in statistics, engineering and other fields.
A. Gelman   +17 more
core   +3 more sources

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