Results 121 to 130 of about 26,437,347 (324)

Function‐driven design of a surrogate interleukin‐2 receptor ligand

FEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang, Zelin Cheng, Teng Li, Fulian Wang, Liangminghui Zhang, Xiuxiu He, Lili Liu, Wei Wang, Aibin Liang, Guang Yang   +9 more
wiley   +1 more source

Corporate business analysis as a vital tool for guiding the strategic growth of economic entities

Учёт. Анализ. Аудит
The scientific school of corporate business analysis at the Financial University defines business analysis as a systematic process to identify and assess business problems, propose solutions, and support the implementation of change projects.
V. I. Barilenko
doaj   +1 more source

Mechanisms of parasite‐mediated disruption of brain vessels

FEBS Letters, EarlyView.
Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira, Sílvia Arroz‐Madeira, Cláudio A. Franco, Sara Silva Pereira   +3 more
wiley   +1 more source

Requirements Analysis Spiral

Defence Science Journal, 2006
Requirements symbolise the need or the set of needs for triggering the development process of the system. The system developed must follow the law of the requirements. Capturing the requirements of a system is a challenge. It is both subjective and objective process.
openaire   +1 more source

Design of a Game-Based Training Environment to Enhance Health Care Professionals' E-Mental Health Skills: Protocol for a User Requirements Analysis.

JMIR Res Protoc, 2021
Bierbooms JJPA, Sluis-Thiescheffer WRJW, Feijt MA, IJsselsteijn WA, Bongers IMB.   +4 more
europepmc   +1 more source

Qualification requirements in Norwegian public libraries – an analysis of job advertisements

, 2021
Beate Bjørklund, Ragnar Audunson
openalex   +1 more source

Time after time – circadian clocks through the lens of oscillator theory

FEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo, Carolin Ector, Hanspeter Herzel   +2 more
wiley   +1 more source

Survey, Analysis, and Requirements for Semantic Enhancement to Support Machine Understanding of Scientific Literature

, 2020

openalex   +2 more sources

Integrated and Iterative Requirements Analysis and Test Specification: A\n Case Study at Kostal [PDF]

, 2021
Carsten Wiecher, Jannik Fischbach, Joel Greenyer, Andreas Vogelsang, Carsten Wolff, Roman Dumitrescu   +5 more
openalex   +1 more source

Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions

FEBS Letters, EarlyView.
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf, Nicholas F. Downing, Kaitlyn M. Mills, Samuel C. Metcalfe, Alexander E. Kritzer, Lindsey D. Mayo, Peter C. Hollenhorst   +6 more
wiley   +1 more source