Results 121 to 130 of about 276,201 (318)
Lipid Nanoparticle‐Mediated CRISPR‐Cas13a Delivery for the Control of Bacterial Infection
Advanced Healthcare Materials, Volume 14, Issue 7, March 14, 2025.New formulations of lipid nanoparticles (LNPs) that can deliver nucleic acids to Gram‐negative bacteria are proposed to combat bacterial infection. The delivery of nucleic acids by LNPs is aided by LNP‐helpers which weaken the bacterial outer membrane. LNPs encapsulating the Cas13a/gRNA expression vector achieve an antibacterial effect in both in vivo ...
Bookun Kim +9 more
wiley +1 more source
Problem-Focused Incremental Elicitation of Multi-Attribute Utility Models [PDF]
arXiv, 2013 Decision theory has become widely accepted in the AI community as a useful framework for planning and decision making. Applying the framework typically requires elicitation of some form of probability and utility information. While much work in AI has focused on providing representations and tools for elicitation of probabilities, relatively little ...
arxiv
Advanced Healthcare Materials, Volume 14, Issue 7, March 14, 2025.The top‐performing lipid nanoparticle, incorporating a novel ionizable lipid derived from vitamin B5, demonstrates high mRNA transfection efficiency, low toxicity, favorable stability, targeted delivery to lymphoid tissues, and high immunogenicity, showing promise as a carrier for mRNA vaccines for infectious diseases and cancer.
Soyeon Yoo +11 more
wiley +1 more source
The Elicitation Game: Evaluating Capability Elicitation Techniques [PDF]
arXivCapability evaluations are required to understand and regulate AI systems that may be deployed or further developed. Therefore, it is important that evaluations provide an accurate estimation of an AI system's capabilities. However, in numerous cases, previously latent capabilities have been elicited from models, sometimes long after initial release ...
arxiv
Next generation social networks - elicitation of user requirements [PDF]
, 2008 Lars Schiøtt Sørensen +1 more
openalex +1 more source
Liquid Crystalline Networks Hamper the Malignancy of Cancer Cells
Advanced Healthcare Materials, Volume 14, Issue 7, March 14, 2025.Liquid Crystalline Networks are used as scaffolds for the growth of A375 melanoma cells demonstrating to affect their malignancy. Indeed, only by contact, these materials reduces cell proliferation and colony formation capacity, while increasing the number of senescent cells and promoting the mesenchymal to epithelial transition.
Daniele Martella +9 more
wiley +1 more source
Eliciting User Input for Requirements on Personalization [PDF]
, 2008 Lex van Velsen +2 more
openalex +1 more source
Advanced Healthcare Materials, EarlyView.NeoCast is a next‐generation, solvent‐free, non‐adhesive liquid embolic designed for indications where deep occlusion is desired (e.g., tumors and chronic subdural hematoma). This novel agent offers ideal embolic properties: injectability, controllability, excellent visibility, and biocompatibility.
Quynh P. Pham +16 more
wiley +1 more source
Advanced Healthcare Materials, EarlyView.Minimal residual disease (MRD) leads to cancer relapse and poor survival in ovarian cancer. The lack of representative 3D models limits therapy development. The microfluidics‐based high throughput 3D microtumor platform described here generates clinically‐relevant MRD models. The 3D microtumors recapitulate the molecular signatures of MRD from patients.
Xingyun Yang +14 more
wiley +1 more source
Developing a Requirements Model for Software Projects
Ibn Al-Haitham Journal for Pure and Applied SciencesRequirements elicitation is recognized as one of the most critical activities in the software development process as it has an impact on its success. Studies such as the CHAOS Report, a study based on The [Standish Group]'s CHAOS Research Project on IT ...
Ali Yahya Gheni +3 more
doaj +1 more source