Results 151 to 160 of about 276,201 (318)

Dendrimer Conjugates with PD‐L1‐Binding Peptides Enhance In Vivo Antitumor Immune Response

open access: yesAdvanced Healthcare Materials, EarlyView.
In this paper, a novel nanoparticle scaffold composed of dendrimers conjugated with peptide‐based immune checkpoint inhibitors, enhancing drug delivery efficacy is introduced. By conjugating PD‐L1‐binding peptides to dendrimers, multivalent binding effects are harnessed, resulting in enhanced binding affinity, prolonged half‐life, and improved ...
DaWon Kim   +11 more
wiley   +1 more source

What’s Special about Requirements Engineering for Quantum-Classical

open access: yesMemoria Investigaciones en Ingeniería
Quantum computing will impact all software development life cycle phases to a greater or lesser extent. With support from current literature, we discuss its potential impact on requirements engineering. We identified four main trends.
Horacio Pendenti   +5 more
doaj  

Biomimetic Scaffolds Enhance iPSC Astrocyte Progenitor Angiogenic, Immunomodulatory, and Neurotrophic Capacity in a Stiffness and Matrix‐Dependent Manner for Spinal Cord Repair Applications

open access: yesAdvanced Healthcare Materials, EarlyView.
Through tuning biomimetic scaffold stiffness and matrix composition the reparative capacity of astrocyte progenitors is enhanced. Soft, collagen‐IV/fibronectin‐functionalized scaffolds promote progenitor growth while improving angiogenic, immunomodulatory, and neurotrophic capacity in a stiffness and matrix‐dependent manner, demonstrating the impact of
Cian O'Connor   +10 more
wiley   +1 more source

Perovskite Light‐Emitting Diodes with Quantum Wires and Nanorods

open access: yesAdvanced Materials, EarlyView.
This review focuses on low‐dimensional perovskite materials and discusses their applications in light‐emitting diodes (LEDs). Special attention is given to the introduction of perovskite quantum wires and nanorods, two unique types of one‐dimensional (1D) materials, and their interesting optoelectronic properties.
Qianpeng Zhang   +11 more
wiley   +1 more source

Accelerated Preference Elicitation with LLM-Based Proxies [PDF]

open access: yesarXiv
Bidders in combinatorial auctions face significant challenges when describing their preferences to an auctioneer. Classical work on preference elicitation focuses on query-based techniques inspired from proper learning--often via proxies that interface between bidders and an auction mechanism--to incrementally learn bidder preferences as needed to ...
arxiv  

Digitonin‐Loaded Nanoscale Metal–Organic Framework for Mitochondria‐Targeted Radiotherapy‐Radiodynamic Therapy and Disulfidptosis

open access: yesAdvanced Materials, EarlyView.
A mitochondria‐targeted cationic nanoscale metal organic framework shows strong radiotherapy‐radiodynamic therapy effects and selectively releases digitonin in acidic tumor microenvironments to induce disulfidptosis of cancer cells and downregulate immune checkpoints in cancer and T cells, thereby eliciting strong antitumor immunity to effectively ...
Wenyao Zhen   +7 more
wiley   +1 more source

Using Concepts of CSCW to Validate Requirements Elicited for a Brazilian Geographic Information System [PDF]

open access: bronze, 2014
Danilo Sousa   +4 more
openalex   +1 more source

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