Results 61 to 70 of about 276,201 (318)

B cell mechanobiology in health and disease: emerging techniques and insights into therapeutic responses

FEBS Letters, EarlyView.
B cells sense external mechanical forces and convert them into biochemical signals through mechanotransduction. Understanding how malignant B cells respond to physical stimuli represents a groundbreaking area of research. This review examines the key mechano‐related molecules and pathways in B lymphocytes, highlights the most relevant techniques to ...
Marta Sampietro, Marco Cellani, Cristina Scielzo   +2 more
wiley   +1 more source

An Investigation of Prototyping Technique in Pakistani Software Industry

Mehran University Research Journal of Engineering and Technology, 2019
Requirements elicitation is one of the important and major activities within the Requirements Engineering phase. There are different techniques used for requirement elicitation process.
Muhammad Janas Khan, Rafiq Ahmad Khan
doaj  

A Systematic Review of AI-Enabled Frameworks in Requirements Elicitation

IEEE Access
Employing Artificial Intelligence techniques to address challenges in requirements elicitation is gaining traction. Although nine systematic literature reviews have been published on AI-based solutions in the requirements elicitation domain, to our ...
Vaishali Siddeshwar, Sanaa Alwidian, Masoud Makrehchi   +2 more
doaj   +1 more source

Responsibilities in the Usability Requirements Elicitation Process [PDF]

Journal of Systemics, Cybernetics and Informatics, 2008
Like any other software system quality attribute, usability places requirements on software components. In particular, it has been demonstrated that certain usability features have a direct impact throughout the software process.
Marianella Aveledo, Ana M. Moreno
doaj  

Targeting the MDM2‐MDM4 interaction interface reveals an otherwise therapeutically active wild‐type p53 in colorectal cancer

Molecular Oncology, EarlyView.
This study investigates an alternative approach to reactivating the oncosuppressor p53 in cancer. A short peptide targeting the association of the two p53 inhibitors, MDM2 and MDM4, induces an otherwise therapeutically active p53 with unique features that promote cell death and potentially reduce toxicity towards proliferating nontumor cells.
Sonia Valentini, Giada Mele, Marika Attili, Maria Rita Assenza, Fulvio Saccoccia, Francesca Sardina, Cinzia Rinaldo, Roberto Massari, Nicola Tirelli, Alfredo Pontecorvi, Fabiola Moretti   +10 more
wiley   +1 more source

RAD-XP: Tabletop Exercises for Eliciting Resilience Requirements for Sociotechnical Systems

Systems, 2023
Despite noble intentions, new technologies may have adverse effects on the resilience of the sociotechnical systems into which they are integrated. Our objective was to develop a lightweight method to elicit requirements that, if implemented, would ...
Stephen L. Dorton, Emily Barrett, Theresa Fersch, Andrew Langone, Kelly J. Neville   +4 more
doaj   +1 more source

Elicitation of Adaptive Requirements Using Creativity Triggers: A Controlled Experiment [PDF]

arXiv, 2021
Adaptive systems react to changes in their environment by changing their behavior. Identifying these needed adaptations is very difficult, but central to requirements elicitation for adaptive systems. As the necessary or potential adaptations are typically not obvious to the stakeholders, the problem is how to effectively elicit adaptation-relevant ...
arxiv  

Escape from TGF‐β‐induced senescence promotes aggressive hallmarks in epithelial hepatocellular carcinoma cells

Molecular Oncology, EarlyView.
Chronic TGF‐β exposure drives epithelial HCC cells from a senescent state to a TGF‐β resistant mesenchymal phenotype. This transition is characterized by the loss of Smad3‐mediated signaling, escape from senescence, enhanced invasiveness and metastatic potential, and upregulation of key resistance modulators such as MARK1 and GRM8, ultimately promoting
Minenur Kalyoncu, Dilara Demirci, Sude Eris, Bengisu Dayanc, Ece Cakiroglu, Merve Basol, Merve Uysal, Gulcin Cakan‐Akdogan, Fang Liu, Mehmet Ozturk, Gökhan Karakülah, Serif Senturk   +11 more
wiley   +1 more source

Prioritizing Software Requirements by Combining the Usage Monitoring and User Feedback Data

IEEE Access
The elicitation of requirements for systems in use is known as continuous requirements elicitation. Monitoring and feedback data have been used in the literature for the continuous elicitation and prioritization of requirements. Frameworks and techniques
Syeda S. Tanveer, Zeeshan A. Rana
doaj   +1 more source

Systematizing requirements elicitation technique selection [PDF]

Information and Software Technology, 2014
Context: This research deals with requirements elicitation technique selection for software product requirements and the overselection of open interviews. Objectives: This paper proposes and validates a framework to help requirements engineers select the most adequate elicitation techniques at any time.
Carrizo Moreno, Dante Hugo, Dieste Tubio, Óscar, Juristo Juzgado, Natalia   +2 more
openaire   +3 more sources