Results 61 to 70 of about 89,500 (322)

Function‐driven design of a surrogate interleukin‐2 receptor ligand

FEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang, Zelin Cheng, Teng Li, Fulian Wang, Liangminghui Zhang, Xiuxiu He, Lili Liu, Wei Wang, Aibin Liang, Guang Yang   +9 more
wiley   +1 more source

Strategies to Minimize Problems in Global Requirements Elicitation

CLEI Electronic Journal, 2008
Many challenges arise in global software development projects, most of which are related to the lack of face-to-face communication and people’s need to feel comfortable with the technology that they use. In this paper we introduce a methodology to detect
Gabriela N Aranda, Aurora Vizcaíno, Alejandra Cechich, Mario Piattini   +3 more
doaj   +1 more source

Mechanisms of parasite‐mediated disruption of brain vessels

FEBS Letters, EarlyView.
Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira, Sílvia Arroz‐Madeira, Cláudio A. Franco, Sara Silva Pereira   +3 more
wiley   +1 more source

An Investigation of Prototyping Technique in Pakistani Software Industry

Mehran University Research Journal of Engineering and Technology, 2019
Requirements elicitation is one of the important and major activities within the Requirements Engineering phase. There are different techniques used for requirement elicitation process.
Muhammad Janas Khan, Rafiq Ahmad Khan
doaj  

A Systematic Review of AI-Enabled Frameworks in Requirements Elicitation

IEEE Access
Employing Artificial Intelligence techniques to address challenges in requirements elicitation is gaining traction. Although nine systematic literature reviews have been published on AI-based solutions in the requirements elicitation domain, to our ...
Vaishali Siddeshwar, Sanaa Alwidian, Masoud Makrehchi   +2 more
doaj   +1 more source

Effect of domain knowledge on elicitation effectiveness: an internally replicated controlled experiment [PDF]

, 2016
Context. Requirements elicitation is a highly communicative activity in which human interactions play a critical role. A number of analyst characteristics or skills may influence elicitation process effectiveness. Aim.
Aranda López King, Alejandrina, Dieste Tubio, Oscar, Juristo Juzgado, Natalia   +2 more
core   +2 more sources

Issues in Requirements Elicitation [PDF]

, 1992
There are many problems associated with requirements engineering, including problems in defining the system scope, problems in fostering understanding among the different communities affected by the development of a given system, and problems in dealing with the volatile nature of requirements.
Christel, Michael G, Kang, Kyo C
openaire   +1 more source

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham, Jasibel Vasquez‐Gonzalez, Samantha M. Barnada, Salome Tchotorlishvili, Latese Jones, Ryan Maguire, Genevieve Lewis, Kinza Rizwan, Jenny Deng, Salma Koachar, Drithi Patel, Hailey Shankle, Tessa Mulders, Namra Ajmal, Charalambos Solomides, Emad S. Alnemri, Teresa F. Alnemri, Ayesha A. Shafi, Leonard G. Gomella, Wm Kevin Kelly, Steven B. McMahon, Matthew J. Schiewer   +21 more
wiley   +1 more source

Responsibilities in the Usability Requirements Elicitation Process [PDF]

Journal of Systemics, Cybernetics and Informatics, 2008
Like any other software system quality attribute, usability places requirements on software components. In particular, it has been demonstrated that certain usability features have a direct impact throughout the software process.
Marianella Aveledo, Ana M. Moreno
doaj  

Improvement of Requirement Elicitation Process through Cognitive Psychology

Sukkur IBA Journal of Computing and Mathematical Sciences, 2017
Proper requirement elicitation is necessary for client satisfaction along with the overall project success, but requirement engineers face problems in understanding user requirements and the users of the required system fail to make requirement ...
Sana Fatima, Qamar Uddin Khand, Jawaid Ahmed Siddique, Zulfiqar Ali Memon   +3 more
doaj   +1 more source