Results 121 to 130 of about 4,587,708 (353)

Biomarker testing in oncology – Requirements for organizing external quality assessment programs to improve the performance of laboratory testing: revision of an expert opinion paper on behalf of IQNPath ABSL [PDF]

open access: hybrid, 2020
Kelly Dufraing   +20 more
openalex   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Race to the Top: Colorado May Be Used to High Altitudes But Can It Compete in Race to the Top? [PDF]

open access: yes, 2009
Outlines expected requirements for the American Recovery and Reinvestment Act's funding to the states for education reform. Offers strategies for improving teacher quality in Colorado, as well as data infrastructure, low-performing schools, and ...
Kate Walsh, Sandi Jacobs
core  

The newfound relationship between extrachromosomal DNAs and excised signal circles

open access: yesFEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

BUILDING DETERMINISTIC MODELS OF PRODUCT QUALITY DYNAMICS

open access: yesВестник Донского государственного технического университета, 2018
The deterministic models of the product quality dynamics based on the theoretical basics of the material systems kinetics are built. The dependence of the product quality change from the production complexity, resistance factors and requirements of ...
Alexander G. Ivakhnenko   +1 more
doaj  

Comparative Analysis of Compendial Quality Requirements for Carvedilol Products

open access: yesРегуляторные исследования и экспертиза лекарственных средств
INTRODUCTION. Carvedilol is a drug used to treat renovascular hypertension and cardiovascular diseases. A monograph for carvedilol drug substance has been included in the State Pharmacopeia of the Russian Federation (SP RF); however, quality requirements
A. I. Belanova   +2 more
doaj   +1 more source

Drying of Heat Sensitive Materials of High Moisture Content in Mechanically Spouted Bed of Inert Particles [PDF]

open access: yes, 2008
In drying operation the material characteristics such as heat sensitivity, moisture content and particle size are of great importance, which should be taken into account in selection of proper design and conditions for the process.
Gyenis, János   +2 more
core  

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

Cost Effectiveness of Adopted Quality Requirements in Hospital Laboratories

open access: yesIranian Journal of Public Health, 2013
Background: The present study was designed in quasi-experiment to assess adoption of the essential clauses of particular clinical laboratory quality management requirements based on international organization for standardization (ISO 15189) in hospital ...
Alneil Hamza   +4 more
doaj   +2 more sources

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