Results 51 to 60 of about 148,752 (225)

PREDICTION OF SURVIVAL OF HEART FAILURE PATIENTS USING RANDOM FOREST

open access: yesPilar Nusa Mandiri, 2020
Human survival, one of the roles that is controlled by the heart, makes the heart need to be guarded and be aware of its damage. Heart failure is the final stage of all heart disease.
Sri Rahayu   +5 more
doaj   +1 more source

Integrated Transcriptomics Reveals Evolutionary Trajectories and Cell Density‐Dependent Mechanisms in Aldosterone‐Producing Adenomas

open access: yesAdvanced Science, EarlyView.
Aldosterone‐producing adenomas (APAs) develop via two distinct paths: directly from adrenal zona glomerulosa (zG) cells, or stepwise from zG cells through aldosterone‐producing micronodules (APMs) before progressing to APAs. Advanced single‐cell and spatial analyses identified distinct cell states linked to oxidative stress and cell–cell interactions ...
Zhuolun Sun   +7 more
wiley   +1 more source

Unveiling Global Diversity of Patescibacteriota and Functional Interactions with Host Microbes

open access: yesAdvanced Science, EarlyView.
Patescibacteriota represents a diverse group of ultra‐small epibiotic bacteria, which is largely overlooked. By integrating ribosomal protein S3‐based community profiling with MAG‐based metabolic potential analyses, this study provides new insights into their distribution, diversity, and potential interactions with other bacteria across diverse ...
Yanhan Ji   +12 more
wiley   +1 more source

An Algorithmic Proof of the Lovasz Local Lemma via Resampling Oracles

open access: yes, 2015
The Lovasz Local Lemma is a seminal result in probabilistic combinatorics. It gives a sufficient condition on a probability space and a collection of events for the existence of an outcome that simultaneously avoids all of those events.
Harvey, Nicholas, Vondrak, Jan
core   +1 more source

Potent and Long‐Lasting Immunogenicity Generated by LNP‐mRNA gE Antigen Against Varicella Zoster Virus via an AI‐Assisted Pipeline

open access: yesAdvanced Science, EarlyView.
This study designs a novel mRNA‐LNP vaccine targeting VZV glycoprotein E (gE) for herpes zoster via an AI‐assisted pipeline. Validated in mice and rhesus macaques, the mRNA‐LNP vaccine shows strong humoral and cellular immune responses, with CD4+ T‐cell responses more effective and durable than Shingrix, offering a promising prophylactic option ...
Kai Dong   +6 more
wiley   +1 more source

Analysis of sparse data in pharmacokinetic studies

open access: yesФармакокинетика и Фармакодинамика, 2020
Performing pharmacokinetic and statistical analysis in the case of sparse data presents significant difficulties. Using the example of the pharmacokinetic (PK) study of resveratrol in mice, the resampling method was allowed us to obtain individual PK ...
I. I. Miroshnichenko   +3 more
doaj   +1 more source

CLinNET: An Interpretable and Uncertainty‐Aware Deep Learning Framework for Multi‐Modal Clinical Genomics

open access: yesAdvanced Science, EarlyView.
Identifying disease‐causing genes in neurocognitive disorders remains challenging due to variants of uncertain significance. CLinNET employs dual‐branch neural networks integrating Reactome pathways and Gene Ontology terms to provide pathway‐level interpretability of genomic alterations.
Ivan Bakhshayeshi   +5 more
wiley   +1 more source

OPTRACE: Optical Imaging–Guided Transplantation and Tracking of Cells in the Mouse Brain

open access: yesAdvanced Science, EarlyView.
OPTRACE establishes an optical, two‐step platform for intracerebral cell therapy. Transparent glass pipettes enable real‐time, image‐guided delivery, while multiplex genetic labeling with two‐photon and bioluminescence readouts supports longitudinal single‐cell tracking and host–graft dynamics.
Jinghui Wang   +10 more
wiley   +1 more source

A bootstrapped neural network model applied to prediction of the biodegradation rate of reactive Black 5 dye - doi: 10.4025/actascitechnol.v35i3.16210

open access: yesActa Scientiarum: Technology, 2013
Current essay forwards a biodegradation model of a dye, used in the textile industry, based on a neural network propped by bootstrap remodeling. Bootstrapped neural network is set to generate estimates that are close to results obtained in an intrinsic ...
Kleber Rogério Moreira Prado   +5 more
doaj   +1 more source

Comparison of Resampling Schemes for Particle Filtering

open access: yes, 2005
This contribution is devoted to the comparison of various resampling approaches that have been proposed in the literature on particle filtering. It is first shown using simple arguments that the so-called residual and stratified methods do yield an ...
Cappé, Olivier   +2 more
core   +2 more sources

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