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Molecules, 2023 Cell viability and metabolic activity are ubiquitous parameters used in biochemistry, molecular biology, and biotechnological studies. Virtually all toxicology and pharmacological projects include at some point the evaluation of cell viability and/or ...
MIGUEL A R B Castanho +1 more
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Revisiting the Resazurin-Based Sensing of Cellular Viability: Widening the Application Horizon
Biosensors, 2022 Since 1991, the NAD(P)H-aided conversion of resazurin to fluorescent resorufin has been widely used to measure viability based on the metabolic activity in mammalian cell culture and primary cells.
Maris-Johanna Tahk +2 more
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Standard Operating Procedure to Optimize Resazurin-Based Viability Assays [PDF]
BiosensorsThe resazurin assay, also known as the Alamar Blue assay, stands as a cornerstone technique in cell biology, microbiology, and drug development. It assesses the viability of cells through the conversion of resazurin into highly fluorescent resorufin. The
Jessica Petiti, Carla Divieto
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Role of dipA and pilD in Francisella tularensis Susceptibility to Resazurin
Antibiotics, 2021 The phenoxazine dye resazurin exhibits bactericidal activity against the Gram-negative pathogens Francisella tularensis and Neisseria gonorrhoeae. One resazurin derivative, resorufin pentyl ether, significantly reduces vaginal colonization by Neisseria ...
Kendall Souder +11 more
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Employment of a Resazurin Viability-Based Assay for Minimum Inhibitory and Bactericidal Concentration Determination [PDF]
PharmaceuticalsBackground/Objectives: The increasing prevalence of antimicrobial-resistant bacteria highlights the need for improved methodologies to evaluate antimicrobial activity beyond conventional minimum inhibitory concentration testing.
Lorena G. Calvo +4 more
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Incompatibility of resazurin to detect viable cells in lignin biomaterials: a cautionary study [PDF]
BMC Research NotesObjective The nanoparticles prepared from lignin polymer and its methacrylated derivative have gained significant attention in the biomedical field owing to their superior biosafety profile.
T. Meghana +5 more
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Teneurin C-Terminal Associated Peptide (TCAP)-3 Increases Metabolic Activity in Zebrafish
Frontiers in Marine Science, 2021 Teneurin C-terminal associated peptides (TCAP), bioactive peptides located on the C-terminal end of teneurin proteins, have been shown to regulate stress axis functions due to the high conservation between TCAP and corticotropin releasing factor (CRF ...
Ross M. Reid +4 more
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Frontiers in Chemistry, 2023 Resazurin (Alamar Blue, RZ) is a widely utilized fluorescent probe for biological sensing, whose fluorescent intensity can be modulated by changing its redox states; thereby, electrochemical reactivity of RZ is of significance when designing a sensing ...
Jia Liu +7 more
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Bioengineering, 2023 The resazurin reduction test is one of the basic tests for bacterial culture viability and drug resistance endorsed by the World Health Organisation. At the same time, conventional spectrophotometric and spectrofluorimetric methods demand rather bulky ...
Alexander V. Sychev +3 more
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Biomedicines, 2023 Cancer is a global medical problem and, despite research efforts in the field of tumor treatment, there is currently a shortage of specific anticancer drugs. Most anticancer drugs show significant side effects.
Valeriana Pantea +4 more
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