Results 51 to 60 of about 23,387 (216)

Icariin Enhances the Enzymatic Activity of N‐acetylgalactosaminidase to Augment Akkermansia Abundance in Gut Microbiota for Improved PD‐1 Blockade Efficacy in Tumor Suppression

Advanced Science, EarlyView.
Icariin promoted the growth of Akk by enhancing the activity of N‐acetylgalactosaminidase (Amuc_0920), which enhanced mucin utilization and provided a favorable nutrient environment for bacterial growth. This icariin‐mediated enrichment of Akk further reshaped the tumor microenvironment and promoted CD8+ T cell infiltration, ultimately synergizing with
Shuangying Qiao, Liu Yang, Haibang Hao, Qiuxia Ding, Feng Ding, Zheng Chen, Jinfang Zhang, Yun He, Meng Li, Jun Xu, Chao Wang, Aiping Lu, Fangfei Li   +12 more
wiley   +1 more source

Evaluation of the effect of resazurin adsorbed onto polyacrylic acid hydrogels on cell viability analysis

, 2021
YÖK Tez No: 677383Bu tez, poli akrilik asit hidrojele resazurin boyasının adsorbe edilmesi için koşulların optimizasyonunu ve yüksek verimde hidrojele adsorbe edilmiş resazurinin bakteri ve memeli hücrelerinde canlılık test sonuçları üzerine etkisinin ...
Varçin, Merve
core  

Streptavidins Coordinate Biotin Sequestration and Self‐Resistance Within a Biotin‐Pathway Antibiotic Network

Advanced Science, EarlyView.
A conserved genomic region between two streptavidin genes in Streptomyces packages biosynthetic gene clusters for diverse biotin‐pathway antibiotics: acidomycin, stravidin, the new non‐proteinogenic amino acid ANDA, and the new BioA inhibitor α‐methyl‐KAPA.
Sumire Kurosawa, Jingjun Mo, Xiaotong Diao, Feng Xie, Tingting Wang, Haowen Zhao, Dalei Wu, Rolf Müller, Chengzhang Fu   +8 more
wiley   +1 more source

Standardization of resazurin use in susceptibility testing of natural products against yeasts in planktonic cells and in biofilms formation

Acta Scientiarum: Biological Sciences, 2021
Natural products, such as the ethanolic propolis extract (PE), have been shown to be a safe and effective therapeutic alternative for the treatment of fungal skin and nail diseases.
Isabella Letícia Esteves Barros, Flávia Franco Veiga, Jakeline Luiz Corrêa, Isabele Carrilho Jarros, Melyssa Negri, Terezinha Inez Estivalet Svidzinski   +5 more
doaj   +1 more source

A new rapid resazurin-based microdilution assay for antimicrobial susceptibility testing of Neisseria gonorrhoeae. [PDF]

, 2017
Objectives Rapid, cost-effective and objective methods for antimicrobial susceptibility testing of Neisseria gonorrhoeae would greatly enhance surveillance of antimicrobial resistance.
Hathaway, Lucy J, Sunniva Foerster, Foerster, Sunniva,, Desilvestro, Valentino,, Althaus, Christian L, Hathaway, Lucy J,, Christian L. Althaus, Unemo, Magnus, Althaus, Christian L,, Lucy J. Hathaway, Desilvestro, Valentino, Magnus Unemo, Foerster, Sunniva, Valentino Desilvestro, Unemo, Magnus,   +14 more
core   +1 more source

Molecular Engineering Mediated Interfacial Assembly as an Artificial Extracellular Matrix Remolds Bacteria With Enhanced Abiotic Resilience

Advanced Science, EarlyView.
A biomimetic artificial extracellular matrix is assembled directly on Pseudomonas fluorescens by co‐assembling amyloid‐like lysozyme and alginate at the cell surface. This conformal nanocoating acts as both a hydration buffer and a physiological priming layer, markedly enhancing desiccation tolerance, seed adhesion, storage stability, and biocontrol ...
Yuanyuan Wang, Zili Jia, Yang Li, Qitao Wang, Shuai Hou, Lei Liu   +5 more
wiley   +1 more source

Resazurin assay of radiation response in cultured cells

, 2005
We describe use of resazurin reduction for measurement of cell response to irradiation as a simple and non-destructive assay that complements the conventional colony forming assay and can readily be applied to both adherent and non-adherent cell cultures.
Anoopkaumar-Dukie, S, O⿿Sullivan, E, Carey, J, van Pelt, F, Allshire, A, O'Sullivan, E, van Pelt, FN, Carey, JB, Conere, T, Anoopkumar-Dukie, S   +9 more
core   +1 more source

Time-dependent resazurin reduction by T. cruzi trypomastigotes at different cell densities.

, 2023
Trypomastigotes were obtained as indicated in the methods section and prior to the resazurin assay, were incubated for 24 (panel A) and 48 hours (panel B) at 37°C.
Luis M. Ruiz-Pérez (699652), Frederick Annang (5428187), Miguel Navarro (176103), Francisca Vicente (484392), Guiomar Pérez-Moreno (843822), Cristina Bosch-Navarrete (740114), Raquel García-Hernández (292595), Ana Rodriguez (266842), Francisco Gamarro (292598), Dolores González-Pacanowska (501255), Olga Genilloud (601676), Rosario Diaz-Gonzalez (345689), Hedy Rocha (16993549), Carlos Cordón-Obras (16993552), Fernando Reyes (444361)   +14 more
core   +1 more source

Liposomal Delivery of L‐2‐Hydroxyglutarate for Targeting Epigenetic Dysregulation in Osteoarthritis

Advanced NanoBiomed Research, EarlyView.
Osteoarthritis involves cartilage degeneration, inflammation, and epigenetic dysregulation. A liposomal formulation of the TET1 inhibitor L‐2‐hydroxyglutarate to overcome rapid joint clearance was developed. The formulation showed good physicochemical properties, reduced inflammatory and catabolic gene expression in chondrocytes, and alleviated ...
Denise Murgia, Akshay Pandey, Raffaele Spanò, Bianca Martins Estevão, Roberto Palomba, Greta Avancini, Tamaghna Gupta, Ana Maria Lopez Estevez, Stuart B. Goodman, Nidhi Bhutani, Paolo Decuzzi   +10 more
wiley   +1 more source

The Antipsychotic Aripiprazole Induces Cytotoxicity in Bladder Cancer Cells While Preserving Urothelial and Bladder Function. [PDF]

Pharmacol Res Perspect
Current bladder cancer therapies can cause toxicity and bladder dysfunction. Brief intravesical‐like aripiprazole exposure reduced bladder cancer cell viability and was associated with redox stress and caspase‐3 activation, while ex vivo findings suggested preserved bladder structure and function, warranting further investigation as a potential ...
O'Callaghan LA, Powell K, Chess-Williams R, McDermott C.   +3 more
europepmc   +2 more sources