Results 71 to 80 of about 881,422 (304)
Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions
FEBS Letters, EarlyView.We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva +10 more
wiley +1 more source
Нештатные аварийно-спасательные формирования в высших учебных заведениях [PDF]
, 2017 В данной статье рассмотрена процедура создания нештатных аварийно-спасательных формирований на базе высших учебных заведений, проблемы, возникающие при организации работы и аттестации нештатных аварийно-спасательных формирований и актуальность этой ...
Романцов, Игорь Иванович +1 more
core
Structural biology of ferritin nanocages
FEBS Letters, EarlyView.Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
Memory frictions and reconciliation: Neo-victorian gothic and gender violence in Katy Darby’s The Whores’ Asylum (2012) [PDF]
, 2015 Katy Derby’s first novel, The Whores’ Asylum (2012), is an attempt to deal with the issue of prostitution and rescue work in Oxford in the 1880s. Jericho is an area where, away from the prestigious university colleges, drunkards, thieves and prostitutes ...
Romero-Ruiz, Maria Isabel
core
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Fire risk assessment – from property to people [PDF]
, 2014 Two studies sponsored by the Nottinghamshire Fire and Rescue Service, one into the assessment and management of risk, and the other on effective communication, picked up the top two prizes in this year’s Fire Related Research and Developments ...
Greenhalgh, K, Murphy, P
core
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Journal of Occupational Medicine and ToxicologyBackground Rescue services work is in constant change, yet operational responsibilities in high-stakes, unpredictable environments remain. In this study, we are interested in individual psychological performance, conceptualized as a balance between the ...
Hilla Nordquist, Sanna Korpela
doaj +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Coal Mine Safety and Health [PDF]
, 2008 [Excerpt] Safety in the coal mining industry is much improved compared to the early decades of the twentieth century, a time when hundreds of miners could lose their lives in a single accident and more than 1,000 fatalities could occur in a single year ...
Levine, Linda
core +4 more sources