Results 181 to 190 of about 51,656,893 (291)

Managing linguistic obstacles in multidisciplinary, multinational, and multilingual research projects. [PDF]

PLoS One
Specht A, Stall S, Machicao J, Catry T, Chaumont M, David R, Devillers R, Edmunds R, Jarry R, Mabile L, Miyairi N, O'Brien M, Correa PP, Santos S, Subsol G, Wyborn L.   +15 more
europepmc   +1 more source

Partial FAK suppression promotes tumor growth, an effect reversed by macrophage p110δ PI3K inactivation

Molecular Oncology, EarlyView.
Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou, Niki Tzenaki, Anna Tsapara, Maria Tzardi, Evangelia A. Papakonstanti   +4 more
wiley   +1 more source

Characterizing redundancy in pharmacy residency research projects. [PDF]

Am J Health Syst Pharm
Yeager LS, Behal M, Flannery AH, Ali D, Livingston J, Woodward B, Cook AM.   +6 more
europepmc   +1 more source

Determining the benefits and drawbacks of parents using personal connections and social networks for recruitment in research projects: a qualitative study. [PDF]

Res Involv Engagem, 2023
Kim L, Costello C, Golding MA, Janse van Rensburg C, Protudjer JLP, Wittmeier K.   +5 more
europepmc   +1 more source

Unraveling the epigenetic code in cancer cell–tumor microenvironment crosstalk

Molecular Oncology, EarlyView.
Epigenetic regulation is a key driver of cancer development and progression. Diverse epigenetic alterations in cancer cells and components of the tumor microenvironment (TME) orchestrate their communication through multiple mechanisms. We discuss how the epigenetic code coordinates bidirectional cancer cell–TME crosstalk to promote cancer progression ...
Ji Hoon Park, Mi‐Young Kim
wiley   +1 more source

The Sailboat Activity: An Interactive, Visually Engaging Approach to Design and Assess Health Profession Education Research Projects. [PDF]

MedEdPORTAL
Harz D, Kesselheim J, Fischer K.
europepmc   +1 more source

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

Molecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic, Rafael Stroggilos, Mladen Marinkovic, Ana Djuric, Suzana Stojanovic‐Rundic, Radmila Jankovic, Sergi Castellvi‐Bel, Remond J.A. Fijneman, Antonia Vlahou, Jerome Zoidakis, Milena Cavic   +10 more
wiley   +1 more source

Mandatory research projects during medical specialist training in Australia and New Zealand: a survey of trainees' experiences and reports. [PDF]

Med J Aust
Stehlik P, Withers C, Bourke RC, Barnett AG, Brandenburg C, Noble C, Bannach-Brown A, Keijzers GB, Scott IA, Glasziou PP, Veysey EC, Mickan S, Morgan M, Joshi H, Forrest K, Campbell TG, Henry DA.   +16 more
europepmc   +1 more source

Predictive and prognostic biomarkers of Bacillus Calmette‐Guérin therapy failure in bladder cancer patients: A systematic review

Molecular Oncology, EarlyView.
High‐risk bladder cancer is typically treated with Bacillus Calmette‐Guérin (BCG), but 30–40% of patients relapse. No FDA‐ or CE‐approved biomarkers currently predict or prognosticate BCG failure. We systematically reviewed the literature and identified 72 eligible studies, revealing several promising biomarkers associated with BCG treatment response ...
Rui Ribeiro‐Pereira, Ana Teixeira‐Marques, Rui Freitas, João A Carvalho, Sara Monteiro‐Reis, Giorgio I. Russo, Rui Henrique, Carmen Jerónimo   +7 more
wiley   +1 more source

Ten simple rules for successfully carrying out funded research projects. [PDF]

PLoS Comput Biol
Forero DA, Curioso WH, Wang W.
europepmc   +1 more source