Results 71 to 80 of about 1,301,492 (295)

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Cortical Models for Movement Control [PDF]

, 2000
Defense Advanced Research Projects Agency and Office of Naval Research (N0014-95-l-0409)
Bullock, Daniel
core   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

FEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel, Carl P. O. Helmer, Shani Zev, Ronja Driller, Emily Buhr, Markus Reinbold, Renana Schwartz, Gabriel Foley, Mikael Boden, Daniel Garbe, Gerhard Schenk, Dan Thomas Major, Bernhard Loll, Thomas Brück   +13 more
wiley   +1 more source

An exact solution for rest-period voltage relaxation in Li-ion batteries for applications on battery management systems

iScience
Summary: Rest-period voltage relaxation in lithium-ion batteries is a non-invasive means to probe the battery’s state of charge (SOC) and health without service interruption. However, to apply voltage relaxation as a reliable method for state estimation,
Sagar Bharathraj, Shashishekar P. Adiga, K. Subramanya Mayya   +2 more
doaj   +1 more source

Effects of compost and digestate on environment and plant production – results of two research projects [PDF]

, 2008
A yearly amount of 9.3x106t compost and digestate derived from separately collected organic waste is produced in the 25 European Union member states. The improvement of soil properties is a major benefit of compost application.
Berner, Alfred, Fuchs, Jacques G., Kupper, Thomas, Mayer, Jochen, Schleiss, Konrad   +4 more
core  

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

University management: Technology for monitoring the reputation of an educational brand

Образование и наука
Introduction. The processes of formation of a multipolar world lead to changes in higher education. An important consequence of the ongoing changes is the reorientation of the activities of universities to the domestic market, the development of new ...
T. D. Sinyavets, E. A. Luneva, N. V. Katunina   +2 more
doaj   +1 more source

Managing and developing distributed research projects in software engineering by means of action-research

Revista Facultad de Ingeniería Universidad de Antioquia, 2013
Participation in software research projects involving several organizations (research groups, enterprises, etc) scattered all around the world is an increasingly frequent phenomenon.
Francisco J. Pino, Mario Piattini, Guilherme Horta Travassos   +2 more
doaj   +1 more source

Chemical research projects office functions accomplishments programs [PDF]

Basic and applied research in the fields of polymer chemistry, polymeric composites, chemical engineering, and biophysical chemistry is summarized.
Heimbuch, A. H., Parker, J. A.
core   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source