Results 91 to 100 of about 14,722,971 (292)

Developing the Research Idea

open access: yesJournal of Investigative Surgery, 2011
After the interest in surgical research, developing the research idea is of fundamental importance because without it we can not have research. Where do the research ideas come from then? Is there any better way to improve our ability to generate research ideas? Where do they come from? What are the factors that stimulate the research idea? Anything we
openaire   +2 more sources

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Research and Development as an Investment [PDF]

open access: yes, 1989
About 20 percent of the gross investment expenditures of U.S. manufacturing firms is expenditures on research and development. Like investment in physical capital, R&D also responds to news about future prospects of the firm, such as profitability, technological opportunities, or changes in factor prices.
Hall, Bronwyn H., Hayashi, Fumio
openaire   +2 more sources

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Manifesto for medical research [PDF]

open access: yes, 2015
The MRCG want to ensure there is a dynamic medical research environment in Ireland. Ensuring priority investment for medical research will help to deliver patient care, public health service transformation and economic and enterprise development.
Medical Research Charities Group
core  

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

open access: yesFEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

RESEARCH AND DEVELOPMENT INVESTMENTS, INNOVATIVE OUTPUT AND FINANCIAL PERFORMANCE OF LISTED CONSUMER GOODS FIRMS IN NIGERIA

open access: yesMalete Journal of Accounting and Finance
As it is generally expected that research and development (R&D) spending should translate into higher financial returns, many listed consumer goods firms in Nigeria continue to record R&D outlays that do not correspond to improved profitability.
Ayobaye Salemcity
doaj   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

open access: yesFEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure   +3 more
wiley   +1 more source

Tendências Recentes do Financiamento à P&D e Implicações sobre a Educação e o Desenvolvimento Econômico

open access: yesRevista de Economia Mackenzie, 2006
The main aim of this paper is to verify whether the world tendency to have the financial capital as the main sponsor of university research is also true in Brazil and the consequences of this move to education and to economic development.
Julia Paranhos   +2 more
doaj  

Ideas for Development in the Americas (IDEA): Volume 2 : September-December, 2003: Working on Labor Markets in Latin America

open access: yes, 2003
The Research Department is pleased to present the latest edition of its newsletter, Ideas for Development in the Americas (IDEA). This issue is based on the IDB\u27s 2004 report on Economic and Social Progress in Latin America, which focuses on the ...
Inter-American Development Bank
core   +1 more source

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