Results 101 to 110 of about 10,811,602 (304)
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
, 2015 Open educational resources, open research, open licenses, data coding and analysis, dissemination of research, digitization, metadata files, and open educational resources for development are some topics outlined and discussed in conference workshops ...
Research on Open Educational Resources for Development (ROER4D)
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Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
FEBS Letters, EarlyView.Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
, 2003 The Research Department is pleased to present the latest edition of its newsletter, Ideas for Development in the Americas (IDEA). This issue is based on the IDB\u27s 2004 report on Economic and Social Progress in Latin America, which focuses on the ...
Inter-American Development Bank
core +1 more source
Revista de Economia Mackenzie, 2006 The main aim of this paper is to verify whether the world tendency to have the financial capital as the main sponsor of university research is also true in Brazil and the consequences of this move to education and to economic development.
Julia Paranhos +2 more
doaj
The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes
FEBS Letters, EarlyView.Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga +3 more
wiley +1 more source
, 2006 Bond development in Latin America presents something of a mixed picture. This edition of IDEA looks at how local bond markets have grown in size and liquidity but continue to lag behind emerging economies in Asia in a number of dimensions.
Inter-American Development Bank
core +1 more source
FEBS Letters, EarlyView.Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source
The next steps : an independent review of sustainable development in the English regions
, 2012 Summarised in 'The next steps : an independent review of sustainable development in the English regions : executive summary'.The Sustainable Development Commission's independent review of the progress of sustainable development in the English regions ...
Sustainable Development Commission
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