Results 121 to 130 of about 10,811,602 (304)

The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome

open access: yesFEBS Letters, EarlyView.
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley   +1 more source

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

open access: yesFEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

Standardization of In-Vitro Evaluation of Extracorporeal Life Support (ECLS) Devices for Research and Development. [PDF]

open access: yesASAIO J
Arens J   +15 more
europepmc   +3 more sources

Cell geometry and membrane protein crowding constrain Escherichia coli growth rate, overflow metabolism, respiration, and maintenance energy

open access: yesFEBS Letters, EarlyView.
The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson   +6 more
wiley   +1 more source

International corporate investment in Ohio operations

open access: yes, 2005
Title from covers of PDF documents (viewed Jun. 10, 2005).; "April, 2005."; Harvested from the web on 6/13/05Introduction and maps (11 p.) -- Leader profiles (12 p.) -- Alphabetical listing of companies (103 p.) -- Alphabetical listing of countries with ...
Ohio. Dept. of Development. Office of Strategic Research
core  

Research for Development : A World Bank Perspective on Future Directions for Research

open access: yes, 2010
This paper provides an overview of the history of development research at the World Bank and points to new future directions in both what we research and how we research. Six main messages emerge.
Development Economics Senior Vice Presidency
core   +1 more source

Academic research – a catalyst for the innovation process within companies in Romania

open access: yesAmfiteatru Economic, 2014
Current economic developments make the use of scientific resources, especially academic research, to be no longer just an option for companies wanting to remain competitive, but a necessity.
Rodica Pamfilie   +2 more
doaj  

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

open access: yesFEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace   +6 more
wiley   +1 more source

Learning from tigers and cubs : economic restructuring in East Asia; lessons for India

open access: yes, 1992
PhotocopyMissing p.4-5, 16-17, 76-77, 86-87, 132-133, 172 ...
Agrawal, Pradeep   +4 more
core  

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