Results 111 to 120 of about 14,722,971 (292)
A study of the major research problems and obstacles and presenting proper procedures for them in Islamic azad uuniversity in Abhar [PDF]
مدیریت بهره وری, 2008 Research is a acientific method of finding solutions to problems and creating knowledge. A society in which scientific belief has become a common culture, seeks scientific solutions to solve a problem.
Farzaneh Khalili, Yadollah Rajaye
doaj
Development of a Research Section [PDF]
Physical Therapy, 1969 M T, Moffroid, J M, Hofkosh
openaire +2 more sources
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
RESEARCH AND DEVELOPMENT IN NURSING [PDF]
Journal of Advanced Nursing, 1992 openaire +3 more sources
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
FEBS Letters, EarlyView.The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
Research, Development and Technology Transfer Program, fiscal year ...
, 2007 Description based on: 2008; title from title screen (viewed on Sept. 26, 2007).; The fiscal year runs from July 1 to June 30.; Harvested from the web on 9/26/07Describes the SPR Part 2 (SPR-2), Research and Development portion of the State Planning and ...
Ohio. Dept. of Transportation.
core
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
The Political Economy of Productivity: Actors, Arenas and Policymaking
, 2009 This presentation was prepared for an IDB Seminar titled "Brainstorming Session: The Political Economy of Productivity: Actors, Arenas, and Policymaking," held on February 6th, 2009.
Inter-American Development Bank
core +1 more source
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source