Results 111 to 120 of about 20,796,969 (276)

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

open access: yesFEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens   +8 more
wiley   +1 more source

Industry 4.0 – Development and Limitations in Large Manufacturing Enterprises in Poland. Analysis of Research Results [PDF]

open access: yes
Theoretical background: Industry 4.0 tools are an important element in achieving a competitive advantage, especially among manufacturing companies. There are numerous studies regarding this idea’s level of implementation in companies operating in Poland ...
Stasiuk-Piekarska, Anna Katarzyna
core   +2 more sources

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

open access: yesFEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi   +6 more
wiley   +1 more source

Journey of a Research Article [PDF]

open access: yesThe Journal of Obstetrics and Gynecology of India, 2018
openaire   +2 more sources

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

The Quest for Citations: Drivers of Article Impact [PDF]

open access: yes
Why do some articles become building blocks for future scholars, while many others remain unnoticed? We aim to answer this question by contrasting, synthesizing and simultaneously testing three scientometric perspectives – universalism, social ...
Stremersch, S.   +2 more
core   +1 more source

Research Issues in Ad-Hoc Distributed Databases [PDF]

open access: yes, 2016
Ad-hoc networks are a key in the evolution of wireless networks. Ad-hoc networks are typically composed of equal nodes, which communicate over wireless links without any central control.
Kaur, Jasvir; Research Scholar GNA University,Phagwara   +1 more
core  

Participation of persons living with dementia in research : A means to address epistemic injustice [PDF]

open access: yes
Epistemic injustice refers to wronging or mistreating individuals in terms of their capacity as knowers, based on prejudices or negative attitudes. Excluding people with dementia from research is a form of epistemic injustice. In this article, we discuss
Halonen, Ulla   +3 more
core   +1 more source

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

open access: yesFEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang   +4 more
wiley   +1 more source

TRIPS and plant varietal protection : economic analysis and policy choices [PDF]

open access: yes, 2002
This paper reviews the economic aspects of the options facing developing countries in implementing intellectual property right protection for agricultural plant varieties under the WTO TRIPS agreement (Article 27(3)b).
Eaton, D.
core  

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