Results 111 to 120 of about 119,269,258 (257)
A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma
FEBS Letters, EarlyView.Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos +9 more
wiley +1 more source
FCTC Evaluation : Sri Lanka’s Compliance with Article 6 - Price and Tax Measures to Reduce the Demand for Tobacco [PDF]
, 2016 42p.This briefing note evaluates Sri Lanka’s compliance with Article 6 of the FCTC through its existing policies on tobacco control. Section 2 of the briefing note provides an overview to Article 6 of the FCTC and its recommendations. It also describes
Economics Team, Verité Research
core
The use of critical speech acts in Psychology and Chemistry research papers
Ibérica, 2004 Creating a research space has become increasingly important in today's competitive academic world, where the pressure to publish requires writers to justify publication of their research article (RA) in order present their new claims to the other members
Anna Frances Fagan Vasta +1 more
doaj
KalbotyraIn the recent decades the interpersonal nature of written academic communication has been widely studied in various linguistic/cultural contexts, including Lithuanian.
Anna Ruskan, Greta Maslauskienė
doaj +1 more source
The ubiquitin system in normal and infected germinal center B cells
FEBS Letters, EarlyView.The ubiquitin system plays a central role in germinal center (GC) B cells, influencing differentiation to long‐lived memory B cells. Oncogenic gammaherpesviruses gain access to memory B cells by establishing latency in GC B cells. Mapping ubiquitin mechanisms in normal and infected GC B cells will define specific molecular circuits in B cells germane ...
Destiny Davis +2 more
wiley +1 more source
PARAMETERS OF WRITING RESEARCH PAPERS BY MULTIPLE AUTHORS: WHO WRITES WHAT TO WHOM? [PDF]
Asian Journal of University Education, 2017 This study investigated the writing parameters of a research paper by multiple authors who formed a research team in a public university in Malaysia.
Ali Derahvasht, Moses Samuel
doaj
Neutralization of the PTX3/CD44 axis suppresses TGF‐β1 signaling in kidney fibrosis
FEBS Letters, EarlyView.This study investigates how the PTX3/CD44 axis promotes kidney fibrosis by activating TGF‐β1 signaling. We demonstrate that the neutralizing antibody WHC‐001 effectively inhibits this pathway, suppressing myofibroblast activation and partial epithelial–mesenchymal transition (EMT).
Chao‐Chun Cheng +8 more
wiley +1 more source
Inhibition of dipeptidyl peptidase 7 impairs lysophagy in LLOMe‐treated HepG2 cells
FEBS Letters, EarlyView.DPP7 inhibition delays ubiquitin‐dependent lysophagy by attenuating ubiquitin accumulation and the recruitment of SQSTM1 and LC3 to damaged lysosomes, resulting in delayed clearance of damaged lysosomes and impaired restoration of lysosomal homeostasis. Created using FigureLabs (Certificate ID: FL‐PUB‐20260922‐Z99XNX).
Na Yeon Park +8 more
wiley +1 more source
Conceptualisations of sex and gender in oral health research [PDF]
Sex and gender are widely recognised as determinants of health, influencing general and oral health outcomes. In this conceptual article, we argue that the potential of sex- and gender-based oral health research to deliver transformative insights into ...
Neville, P, Muirhead, V
core +1 more source
DNA ligase LigE increases bacterial transformation with damaged extracellular DNA
FEBS Letters, EarlyView.The DNA ligase LigE from the naturally competent Gram‐negative bacterium Neisseria gonorrhoaea increases transformation with cut extracellular DNA. This process is ATP‐dependent and relies on the catalytic activity of LigE; it also requires that LigE contains an intact periplasmic localisation sequence, indicating that ligE functions in the periplasm ...
Jolyn Pan +4 more
wiley +1 more source