Results 101 to 110 of about 29,857,715 (400)

Towards Research Excellence for Development: The Research Quality plus (RQ+) Assessment Instrument [PDF]

, 2014
This document presents a framework and practical guidelines for assessing the quality of research for development. Referred to as the "RQ+"1 assessment instrument, it serves as a tool to guide the work of external evaluators hired by IDRC as part of the ...

core  

Purification tags markedly affect self‐aggregation of CPEB3

FEBS Letters, EarlyView.
Although recombinant proteins are used to study protein aggregation in vitro, uncleaved tags can interfere with accurate interpretation. Our findings demonstrate that His₆‐GFP and His₁₂ tags significantly affect liquid droplet and amyloid fibril formation in the intrinsically disordered region (IDR) of mouse cytoplasmic polyadenylation element‐binding ...
Harunobu Saito, Yujin Lee, Motoharu Ueno, Naotaka Sekiyama, Masatomo So, Ayako Furukawa, Kenji Sugase   +6 more
wiley   +1 more source

Citation distributions and research evaluations: The impossibility of formulating a universal indicator

Journal of Data and Information Science
To analyze the diversity of citation distributions to publications in different research topics to investigate the accuracy of size-independent, rank-based indicators.
Rodríguez-Navarro Alonso
doaj   +1 more source

Research assessment in the humanities: problems and challenges [PDF]

, 2010
Research assessment is going to play a new role in the governance of universities and research institutions. Evaluation of results is evolving from a simple tool for resource allocation towards policy design.
Galimberti Paola,
core  

Circulating histones as clinical biomarkers in critically ill conditions

FEBS Letters, EarlyView.
Circulating histones are emerging as promising biomarkers in critical illness due to their diagnostic, prognostic, and therapeutic potential. Detection methods such as ELISA and mass spectrometry provide reliable approaches for quantifying histone levels in plasma samples.
José Luis García‐Gimenez, Juan Carlos Ruiz‐Rodríguez, Ricard Ferrer, Raquel Durá, Antonio Artigas, Iván Bajaña, David Bolado López de Andujar, Irene Cánovas‐Cervera, Adrián Ceccato, Luis Chiscano‐Camón, Elena Climent‐Martinez, Georgia García Fernández, Gemma Goma, Verónica Monforte, Beatriz Quevedo‐Sánchez, Adolf Ruiz‐Sanmartín, Antonio Sierra‐Rivera, Nieves Carbonell Monleón   +17 more
wiley   +1 more source

Bibliometria sì, bibliometria no: la valutazione della ricerca nelle scienze umane e sociali al bivio

AIB Studi, 2014
Il contributo discute della recente proposta dell'ANVUR di creare una banca dati bibliografica e bibliometrica per le scienze umane e sociali. Il dibattito che è seguito alla proposta dell'ANVUR ha messo in luce, ancora una volta, come le scienze umane e
Maria Cassella
doaj   +1 more source

SPARKPLUS for Self- and Peer Assessment on Group-Based Honours’ Research Projects [PDF]

, 2010
This paper explores an application of an online tool SPARKPLUS (Self and Peer Assessment Resource Kit) for the self and peer assessment on the group-based Honours’ research projects.
Chanda, E., Willison, J., Wu, C.
core   +1 more source

Insights into pegRNA design from editing of the cardiomyopathy‐associated phospholamban R14del mutation

FEBS Letters, EarlyView.
This study reveals how prime editing guide RNA (pegRNA) secondary structure and reverse transcriptase template length affect prime editing efficiency in correcting the phospholamban R14del cardiomyopathy‐associated mutation. Insights support the design of structurally optimized enhanced pegRNAs for precise gene therapy.
Bing Yao, Qiangbing Yang, Christian J.B. Snijders Blok, Mark A. Daniels, Pieter A. Doevendans, Raymond Schiffelers, Joost P.G. Sluijter, Zhiyong Lei   +7 more
wiley   +1 more source

Intron‐oriented HTLV‐1 integration in an adult T‐cell leukemia/lymphoma cell line sustains expression of intact ift81 mRNA

FEBS Letters, EarlyView.
In the adult T‐cell leukemia/lymphoma (ATL) cell line ED, the human T‐cell leukemia virus type 1 (HTLV‐1) provirus was integrated into the intron of the ift81 gene in the antisense orientation. Despite this integration, both the intact ift81 and the viral oncogene hbz were simultaneously expressed, likely due to the functional insufficiency of viral ...
Mayuko Yagi, Yuka Hirosawa, Yusaku Sagisaka, Minami Hama, Satoshi Takeda, Jun A. Komano   +5 more
wiley   +1 more source

How and why eLife selects papers for peer review

eLife
When deciding which submissions should be peer reviewed, eLife editors consider whether they will be able to find high-quality reviewers, and whether the reviews will be valuable to the scientific community.
eLife Editorial Leadership, eLife Senior Editors, eLife Early Career Advisory Group   +2 more
doaj   +1 more source