Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
FEBS Letters, EarlyView.Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
Volume isn't openness: misaligned assessment and Open Science adoption in Ecuador
Frontiers in Research Metrics and AnalyticsOpen Science aims to make research more transparent, reusable, and socially valuable, yet adoption may lag where assessment emphasizes journal prestige over openness.
Julio Guerra +2 more
doaj +1 more source
FEBS Letters, EarlyView.Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas +3 more
wiley +1 more source
Teaching Competency of Teacher of Building Drawing Skill In SMK N 1 Sedayu Bantul [PDF]
, 2011 Teacher is an important element for the improvement of Indonesia’s education because teacher has a role to delivery subject matter directly to the student. The teacher must have good teaching competency so the aim of learning can be achieved.
Dian Mei Mulyasari, Dian Mei Mulyasari
core
An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane
FEBS Letters, EarlyView.Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa +3 more
wiley +1 more source
An integrated approach : holistic assessment of vocational trainees in the NZ dairy farming industry : a thesis presented in partial fulfilment of the requirements for the degree of Master of Education (Tertiary Education) at Massey University, Manawatu, New Zealand [PDF]
, 2016 Vocational training qualifications in New Zealand have undergone significant change since 2008 due to the Targeted Review of Qualifications (TRoQ) initiated by the New Zealand Qualifications Authority (NZQA).
Couper, Graeme William
core
Molecular Oncology, EarlyView.ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang +8 more
wiley +1 more source
Development and validation for research assessment of Oncotype DX® Breast Recurrence Score, EndoPredict® and Prosigna®. [PDF]
NPJ Breast Cancer, 2021 Buus R +12 more
europepmc +1 more source
Responsible Research Assessment and Research Information Management Systems
EncyclopediaIn the context of open science, universities, research-performing and funding organizations and authorities worldwide are moving towards more responsible research assessment (RRA). In 2022, the European Coalition for Advancing Research Assessment (CoARA)
Joachim Schöpfel, Otmane Azeroual
doaj +1 more source