Results 131 to 140 of about 72,787,703 (302)
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
An overview of the ongoing debate on the reform of research and researcher assessment is complemented by case studies from the ENLIGHT partner universities.
[missing], ENLIGHT RISE Research Assessment Working Group +1 more
core +1 more source
Grand Challenges in Measuring and Characterizing Scholarly Impact
Frontiers in Research Metrics and Analytics, 2016 Chaomei Chen
doaj +1 more source
Data Missing Not at Random in Mobile Health Research: Assessment of the Problem and a Case for Sensitivity Analyses. [PDF]
J Med Internet Res, 2021 Goldberg SB, Bolt DM, Davidson RJ.
europepmc +1 more source
FEBS Letters, EarlyView.Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas +4 more
wiley +1 more source
Office of Technology Assessment (OTA) Resources, February 1995
, 1995 This collection of Office of Technology Assessment (OTA) Resources information briefs details assessments and documents completed by OTA and categorized into a variety of topics, including the proliferation of weapons of mass destruction, defense ...
Office of Technology Assessment
core
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
The French HER system and the issue of evaluation
Italian Political Science, 2018 The French higher education and research system is based on a double divide of missions, statuses and recruitment procedures. On one side, over 30 public research organizations – whose permanent scientific staff varies from about 300 to over 12.000 ...
Catherine Paradeise
doaj
Development and validation for research assessment of Oncotype DX® Breast Recurrence Score, EndoPredict® and Prosigna®. [PDF]
NPJ Breast Cancer, 2021 Buus R +12 more
europepmc +1 more source