Results 121 to 130 of about 3,564,396 (291)

Cell wall target fragment discovery using a low‐cost, minimal fragment library

FEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan, Mathew Stanley, Olawale Raimi, Andrew T. Ferenbach, Helge C Dorfmueller, Daan M. F. van Aalten   +5 more
wiley   +1 more source

The Italian Research Assessment Exercises

Italian Political Science, 2018
Italian universities have so far experienced three assessment exercises (2001-3, 2004-10 and 2011-14). The fiscal law approved in December 2016 dictates that from now onwards the reference periods will be quinquennial, reducing the discretionary power so
Daniele Checchi
doaj  

Predictors of Research Assessment Completion in a Latino Sample with Dual Disorders. [PDF]

J Immigr Minor Health, 2020
Herrera L, Markle SL, Fukuda M, Aroca P, Villar A, Wang Y, Dominique G, Umoren O, Alegría M.   +8 more
europepmc   +1 more source

Evidence Based Practice Using Formative Assessment in Library Research Support

, 2015
Jackie Wolstenholme
openalex   +2 more sources

Cell density–dependent nuclear‐cytoplasmic shuttling of SETDB1 integrates with Hippo signaling to regulate YAP1‐mediated transcription

FEBS Letters, EarlyView.
At low cell density, SETDB1 and YAP1 accumulate in the nucleus. As cell density increases, the Hippo pathway is gradually activated, and SETDB1 is associated with increased YAP1 phosphorylation. At high cell density, phosphorylated YAP1 is sequestered in the cytoplasm, while SETDB1 becomes polyubiquitinated and degraded by the ubiquitin–proteasome ...
Jaemin Eom, Jaewoong Jang, Jung Sun Park, Yong‐Kook Kang   +3 more
wiley   +1 more source

Evolving Document Patterns in UK Research Assessment Cycles. [PDF]

Front Res Metr Anal, 2020
Adams J, Gurney K, Loach T, Szomszor M.
europepmc   +1 more source

Research on the Design of Intelligent Recommendation System for Civic and Political Education Content and the Effectiveness Assessment of Students’ Acceptance [PDF]

Jing Wen, Rihui Li
openalex   +1 more source

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

FEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson, Mackenzie K Herroon, Shane Mecca, Laimar C Garmo, Jacob Lindquist, Shrila Rajendran, Steve M. Patrick, Izabela Podgorski   +7 more
wiley   +1 more source

Research Assessment

Measurement and Control, 1998
A S Eadie FInstMC, M Campbell FInstMC, J R Pugh FInstMC   +2 more
openaire   +2 more sources

Analysis for research strategic planning and assessment

, 2015
Masako TORIYA
openalex   +2 more sources