Results 111 to 120 of about 59,054,444 (289)

A model for co-production of knowledge: Creating a Research Forum [Elektronisk resurs]

open access: yes, 2021
Collaborations based on academic–practitioner interactions are not always as straightforward as presented in commonplace transdisciplinary theory. This chapter provides the most important insights from past and ongoing work from a sustainability project ...
Dymitrow, Mirek,   +2 more
core  

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

open access: yesFEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas   +4 more
wiley   +1 more source

Co-production Te Runanga o Ngati Whatua

open access: yes, 2006
This report examines co-production principles as they apply in the health and education activities of Te Runanga o Ngati Whatua. It is Te Runanga’s view that they have engaged in co-production with the Crown.
Kawharu, M, Ngaha, Arapera
core  

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

open access: yesFEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Mondragon Co-operatives - Myth or Model [PDF]

open access: yes, 1982
Co-operatives Research Unit
core   +1 more source

An empirical look at citizen co-production in Australia [PDF]

open access: yes, 2015
Co-production – the contribution of time and effort to the delivery of public services by service-users and  citizens, prompted by or in concert with public sector organisations – is attracting increasing attention from governments and ...
Sophie Yates, John Alford
core  

Epigenetic reprogramming of lineage switching in cancer

open access: yesFEBS Letters, EarlyView.
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı   +4 more
wiley   +1 more source

Co-Production in the Urban Setting: Fostering Definitional and Conceptual Clarity Through Comparative Research

open access: yesUrban Planning
Co-production is a concept which is increasingly popular in the planning field to refer to multi-stakeholder collaboration and partnership with citizens.
Dahae Lee, Patricia Feiertag, Lena Unger
doaj   +1 more source

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