Results 111 to 120 of about 56,063,487 (256)

Risk culture in financial organisations [PDF]

, 2013
Interest in the cultures of organisations and their effects on management practices goes back many years and there is an extensive body of scholarship on this topic. Yet this interest has increased dramatically in the period since 2008. The debate is led
Power, Michael, Palermo, Tommaso, Ashby, Simon   +2 more
core  

Metastatic niche shaped by host factors influences disseminated cancer cell fate

FEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward, Álvaro Ruiz‐Tabas, Patricia Altea‐Manzano   +2 more
wiley   +1 more source

To be, or not to be, part-time in academia

eLife
Part-time working can be beneficial for individual academics, and also for academia as a whole. In addition to improving work-life balance and well-being, the benefits of part-time working include increased motivation, reduced burnout, and workplaces ...
Sinead English, M Emília Santos, Clare Buckley, Chrissy L Hammond, Sarah Lloyd-Fox, Nina F Ockendon-Powell   +5 more
doaj   +1 more source

Smaller is better: nanobodies meet NMR

FEBS Letters, EarlyView.
Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley   +1 more source

The meaning of a word

eLife
A fraught exchange on social media leads a PhD student to reconsider how she conducts research on neuroinclusivity while being neurodivergent herself.
Kirsty Lauder
doaj   +1 more source

The Luck of the Draw: Wellcome's Institutional Fund for Research Culture. [PDF]

Wellcome Open Res, 2023
Lewis-Wilson S, Towers S, Wykeham H.
europepmc   +1 more source

L\u27enseignement supérieur Culture - 2018-2019 [PDF]

L\u27enseignement supérieur Culture désigne le réseau constitué d\u27une centaine d\u27établissements d\u27enseignement (pour la plupart publics) dans les domaines de l\u27architecture, du patrimoine, des arts plastiques et du design, du spectacle vivant,
Ministère de la Culture
core  

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

Molecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce, Simone Bini, Marialuisa Sponziello, Giorgio Grani, Giulia Fiscon, Paola Paci, Lorenzo Farina, Rosa Falcone, Valentina Maggisano, Sebastiano Filetti, Cosimo Durante, Antonella Verrienti   +11 more
wiley   +1 more source

Enhancing research culture in academia: a spotlight on early career researchers. [PDF]

BMC Neurosci, 2023
Chisholm KI, Finelli MJ.
europepmc   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source