Results 71 to 80 of about 2,686,106 (243)
Modelling stem cell differentiation related processes—A practical overview for biologists
FEBS Letters, EarlyView.Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
FEBS Letters, EarlyView.CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
Cogent EducationThis study highlights how caring leadership holds significant potential in making Islamic higher education institutions successful and outstanding research.
Muhammad Walid +5 more
doaj +1 more source
FEBS Letters, EarlyView.Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani +3 more
wiley +1 more source
Employability Schemes for Young People in STEM
ExchangesFollowing the success of Employability Schemes for Young People in STEM: Enabling staff to deliver an enriching experience through research culture development, the next stage was to share good practice with more departments within the University of ...
Craig Carnegie +8 more
doaj +1 more source
FEBS Letters, EarlyView.The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi +6 more
wiley +1 more source
ExchangesWe summarise and reflect on the symposium ‘Let me explain: Reason-giving across disciplines’, held at the University of Warwick's Institute of Advanced Study in June 2024. The event brought together scholars from four faculties to discuss the concept of
Yvette Yitong Wang, Simon Gansinger
doaj +1 more source
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
FEBS Letters, EarlyView.The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
Empowering a Global Community Through Co-Production of a Connected University Research Culture
ExchangesHeriot-Watt University (HWU) is a global university with five academic Schools connected across five campuses. To foster a vibrant and inclusive research culture across the global research community, HWU has invested time and resource to strategically ...
Jemina Napier +2 more
doaj +1 more source