Results 121 to 130 of about 25,624,885 (337)

Reciprocal control of viral infection and phosphoinositide dynamics

open access: yesFEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

Medical libraries’ strategies in research data management: analysis and implications

open access: yesForum Bibliotek Medycznych
This article discusses the involvement of Polish medical libraries in the field of research data management (RDM). It provides an overview of RDM’s development and its introduction in medical libraries.
Szymon Kubik   +3 more
doaj   +1 more source

Big Research Data Integration

open access: yes, 2019
The paper presents a vision about a new paradigm of data integration in the context of the scientific world, where data integration is instrumental in exploratory studies carried out by research teams. It briefly overviews the technological challenges to be faced in order to successfully carry out the traditional approach to data integration.
Bartalesi Lenzi V, Meghini C, Thanos C
openaire   +3 more sources

The anti‐CRISPR protein AcrIE8.1 inhibits the type I‐E CRISPR‐Cas system by directly binding to the Cascade subunit Cas11

open access: yesFEBS Letters, EarlyView.
In this study, we present the structure of AcrIE8.1, a previously uncharacterized anti‐CRISPR protein that inhibits the type I‐E CRISPR‐Cas system. Through a combination of structural and biochemical analyses, we demonstrate that AcrIE8.1 directly binds to the Cas11 subunit of the Cascade complex to inhibit the CRISPR‐Cas system.
Young Woo Kang, Hyun Ho Park
wiley   +1 more source

Sharing research data

open access: yesProsthetics & Orthotics International, 2020
Ramstrand, Nerrolyn   +3 more
openaire   +3 more sources

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