Results 131 to 140 of about 9,204,815 (342)

Developing Research Data Management Services and Support for Researchers: A Mixed Methods Study

open access: yes, 2018
This mixed method study determined the essential tools and services required for research data management to aid academic researchers in fulfilling emerging funding agency and journal requirements.
L. Perrier, L. Barnes
semanticscholar   +1 more source

The anticancer effect of the HDAC inhibitor belinostat is enhanced by inhibitors of Bcl‐xL or Mcl‐1 in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
The pan‐HDAC inhibitor belinostat increases the expression of the pro‐apoptotic proteins Bim, Puma, and Noxa and induces apoptosis in ovarian cancer cell lines and patient‐derived tumor organoids when used at high concentrations. Moreover, inhibiting the anti‐apoptotic proteins Bcl‐xL or Mcl‐1 sensitizes these preclinical models to the cytotoxic effect
Cécilia Thomine   +10 more
wiley   +1 more source

Designing a data infrastructure for catalysis science aligned to FAIR data principles

open access: yesCatalysis Communications, 2022
The UK Catalysis Hub (UKCH) is designing and implementing an infrastructure to facilitate the management of research data produced by researchers, the Catalysis Data Infrastructure (CDI).
Abraham Nieva de la Hidalga   +4 more
doaj  

CGO: utilizing and integrating gene expression microarray data in clinical research and data management [PDF]

open access: bronze, 2002
Klaus Bumm   +8 more
openalex   +1 more source

Introduction to Research Data Management and Open Research

open access: yes, 2020
Introduction to RDM primarily for researchers. Can be seen as primer to all other materials in this catalogue. This presentation was delivered virtually for Universidad Nacional Costa Rica on 7th Dec 2020 as part of a Foundational Data Stewardship Workshop.
openaire   +5 more sources

Systematic profiling of cancer‐fibroblast interactions reveals drug combinations in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Fibroblasts, cells in the tumor environment, support ovarian cancer cell growth and alter morphology and drug response. We used fibroblast and cancer cell co‐culture models to test 528 drugs and discovered new drugs for combination treatment. We showed that adding Vorinostat or Birinapant to standard chemotherapy may improve drug response, suggesting ...
Greta Gudoityte   +10 more
wiley   +1 more source

Data Sharing: International and National Approaches

open access: yesIranian Journal of Information Processing & Management, 2018
Information and Communication Technologies (ICTs) have significant role in producing research data in different scientific fields. These data not only lead to generates fields based on research data but also caused to produce a new paradigm or approach ...
Esmaeil Vaziri, ,
doaj  

Circulating tumor DNA monitoring and blood tumor mutational burden in patients with metastatic solid tumors treated with atezolizumab

open access: yesMolecular Oncology, EarlyView.
In patients treated with atezolizumab as a part of the MyPathway (NCT02091141) trial, pre‐treatment ctDNA tumor fraction at high levels was associated with poor outcomes (radiographic response, progression‐free survival, and overall survival) but better sensitivity for blood tumor mutational burden (bTMB).
Charles Swanton   +17 more
wiley   +1 more source

Identifying Data Sharing and Reuse with Scholix: Potentials and Limitations

open access: yesPatterns, 2020
Summary: The Scholexplorer API, based on the Scholix (Scholarly Link eXchange) framework, aims to identify links between articles and supporting data.
Nushrat Khan   +2 more
doaj  

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