Results 61 to 70 of about 654,709 (293)
Insertion of the FeB cofactor in cNORs lacking metal inserting chaperones
FEBS Letters, EarlyView.Nitric oxide reductase is an enzyme found in the bacterial denitrification pathway. The NOR active site contains a non‐heme iron, often, but not always inserted with the assistance of chaperones. Here, we study the insertion of FeB in the subfamily of cNORs lacking chaperones and found a putative channel, conserved in the family, perhaps enabling the ...
Sofia Appelgren, Pia Ädelroth
wiley +1 more source
Legal Culture and empirical research: improving the socio-legal character of the sociology of law
Oñati Socio-Legal Series, 2022 The aim of this special issue is to present empirical research outcomes and theoretical works that use the concept of legal culture to characterize the approach of the sociology of law.
Carlo Pennisi
doaj
Championing Research Through Design in HRI [PDF]
arXiv, 2019 One of the challenges in conducting research on the intersection of the CHI and Human-Robot Interaction (HRI) communities is in addressing the gap of acceptable design research methods between the two. While HRI is focused on interaction with robots and includes design research in its scope, the community is not as accustomed to exploratory design ...
arxiv
Taurine promotes glucagon‐like peptide‐1 secretion in enteroendocrine L cells
FEBS Letters, EarlyView.Taurine, a sulfur‐containing amino acid, is likely taken up by enteroendocrine L cells via the taurine transporter. This process increases the levels of cytosolic ATP. The increase in intracellular Ca2+ concentrations and glucagon‐like peptide‐1 secretion through membrane depolarization is caused by the closure of ATP‐sensitive potassium channels ...
Yuri Osuga +6 more
wiley +1 more source
Revista Latinoamericana de Tecnología Educativa, 2019 En este artículo presentamos Rayuela 2.0, un marco teórico y una herramienta web pensados para ayudar a investigadores noveles en educación y ciencias sociales, en la generación de diseños de investigación sólidos y bien informados.
Iván Manuel Jorrín-Abellán
doaj +1 more source
Research Design Considerations [PDF]
Journal of Graduate Medical Education, 2016 ‘‘I’d really like to do a survey’’ or ‘‘Let’s conduct some interviews’’ might sound like reasonable starting points for a research project. However, it is crucial that researchers examine their philosophical assumptions and those underpinning their research questions before selecting data collection methods. Philosophical assumptions relate to ontology,
Laura Nimmon +4 more
openaire +3 more sources
FEBS Letters, EarlyView.The NlpC_P60 superfamily of peptidases is recognised by its key role in bacterial cell wall homeostasis. Recently, studies have also described the involvement of NlpC_P60‐like enzymes in bacterial competitive mechanisms and pathogenesis across several lineages.
Catharina dos Santos Silva +1 more
wiley +1 more source
Exploring the Future of Remote User Research [PDF]
arXiv, 2022 The rapid move to remote work due to COVID-19 social distancing policies has slowed or stopped most in-person qualitative user research activities. The limitation on in-person activities has pushed many user researchers to consider how they can continue their research remotely and presents an opportunity for user research teams to (re)design their ...
arxiv
Making tau amyloid models in vitro: a crucial and underestimated challenge
FEBS Letters, EarlyView.This review highlights the challenges of producing in vitro amyloid assemblies of the tau protein. We review how accurately the existing protocols mimic tau deposits found in the brain of patients affected with tauopathies. We discuss the important properties that should be considered when forming amyloids and the benchmarks that should be used to ...
Julien Broc, Clara Piersson, Yann Fichou
wiley +1 more source
Design research, eHealth, and the convergence revolution [PDF]
arXiv, 2019 The Quadruple Aim is a framework which prioritizes four aims, or dimensions of performance, for innovating in the healthcare domain, respectively: 1) enhancing the individual experience of care; 2) improving the work life of health care clinicians and staff; 3) improving the health of populations; and 4) reducing the per capita cost of care.
arxiv