Results 71 to 80 of about 34,823,597 (367)

Design Research and Domain Representation [PDF]

open access: yes, 2009
While diverse theories about the nature of design research have been proposed, they are rarely considered in relation to one another across the broader disciplinary field.
Joseph, Frances
core  

Dendritic cells steering antigen and leukocyte traffic in lymph nodes

open access: yesFEBS Letters, EarlyView.
Dendritic cells are key players in the activation of T cells and their commitment to effector function. In this In a Nutshell Review, we will discuss how dendritic cells guide the trafficking of antigen and leukocytes in the lymph node, thus influencing T‐cell activation processes. Dendritic cells (DCs) play a central role in initiating and shaping the
Enrico Dotta   +3 more
wiley   +1 more source

Review: Henry E. Brady & David Collier (Eds.) (2004). Rethinking Social Inquiry: Diverse Tools, Shared Standards

open access: yesForum: Qualitative Social Research, 2006
The book Rethinking Social Inquiry, edited by Henry E. BRADY and David COLLIER, is a response to a book by KING, KEOHANE and VERBA (1994) that aimed to introduce quantitative standards to qualitative research.
Matthias Catón
doaj  

Design reuse research : a computational perspective [PDF]

open access: yes, 1998
This paper gives an overview of some computer based systems that focus on supporting engineering design reuse. Design reuse is considered here to reflect the utilisation of any knowledge gained from a design activity and not just past designs of ...
Duffy, Alex H.B.   +2 more
core  

How to engage stakeholders in research: design principles to support improvement

open access: yesHealth Research Policy and Systems, 2018
BackgroundClosing the gap between research production and research use is a key challenge for the health research system. Stakeholder engagement is being increasingly promoted across the board by health research funding organisations, and indeed by many ...
A. Boaz   +4 more
semanticscholar   +1 more source

Leveraging current insights on IL‐10‐producing dendritic cells for developing effective immunotherapeutic approaches

open access: yesFEBS Letters, EarlyView.
In vivo IL‐10 produced by tissue‐resident tolDC is involved in maintaining/inducing tolerance. Depending on the agent used for ex vivo tolDC generation, cells acquire common features but prime T cells towards anergy, FOXP3+ Tregs, or Tr1 cells according to the levels of IL‐10 produced. Ex vivo‐induced tolDC were administered to patients to re‐establish/
Konstantina Morali   +3 more
wiley   +1 more source

Visual Research: An Introduction to Research Methodologies in Graphic Design [PDF]

open access: yes, 2005
"Visual Research: An Introduction to Research Methodologies in Graphic Design" is a guide to the practice of researching for graphic design projects. This book explains the key terms and theories that underlie design research; examining the importance of
Bestley, Russ, Noble, Ian
core  

Exploring Research through Design in Animal-Computer Interaction [PDF]

open access: yes, 2017
This paper explores Research through Design (RtD) as a potential methodology for developing new interactive experiences for animals. We present an example study from an on-going project and examine whether RtD offers an appropriate framework for ...
Dawkins M.S.   +7 more
core   +2 more sources

FoxO1 signaling in B cell malignancies and its therapeutic targeting

open access: yesFEBS Letters, EarlyView.
FoxO1 has context‐specific tumor suppressor or oncogenic character in myeloid and B cell malignancies. This includes tumor‐promoting properties such as stemness maintenance and DNA damage tolerance in acute leukemias, or regulation of cell proliferation and survival, or migration in mature B cell malignancies.
Krystof Hlavac   +3 more
wiley   +1 more source

Amiloride, fluoxetine or riluzole to reduce brain volume loss in secondary progressive multiple sclerosis: the MS-SMART four-arm RCT

open access: yesEfficacy and Mechanism Evaluation, 2020
Background: Neuroprotective drugs are needed to slow or prevent neurodegeneration and disability accrual in secondary progressive multiple sclerosis.
Floriana De Angelis   +27 more
doaj   +1 more source

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