Results 31 to 40 of about 52,407,333 (239)

Potential Cross Talk between Autism Risk Genes and Neurovascular Molecules: A Pilot Study on Impact of Blood Brain Barrier Integrity

Cells, 2022
Autism Spectrum Disorder (ASD) is a common pediatric neurobiological disorder with up to 80% of genetic etiologies. Systems biology approaches may make it possible to test novel therapeutic strategies targeting molecular pathways to alleviate ASD ...
Rekha Jagadapillai, Xiaolu Qiu, Kshama Ojha, Zhu Li, Ayman El-Baz, Shipu Zou, Evelyne Gozal, Gregory N. Barnes   +7 more
doaj   +1 more source

O projeto Research Domain Criteria e o abandono da tradição psicopatológica

Revista Latinoamericana de Psicopatologia Fundamental, 2014
O artigo explora os pressupostos epistemológicos do Research Domain Criteria (RDoC) - projeto de investigação empírica dos transtornos mentais, dentro de uma plataforma biológica - promovido pelo National Institute of Mental Health (NIMH).
Rafaela Zorzanelli, Paulo Dalgalarrondo, Cláudio E. M. Banzato   +2 more
doaj   +1 more source

Attribution Retraining Group Therapy and SSRIs Affect Differing Facets of Anxiety Among Chinese Patients with Various Diagnoses: A Single-Center, Prospective Study

Psychiatry and Clinical Psychopharmacology, 2021
Background: The NIMH launched a Research Domain Criteria (RDoC) initiative, which encouraged researchers to shift from traditional categorical conceptions of mental disorders to process-oriented psychological functions described by constructs.
Jingya Kong, Huazhen Xu, Xiaowen Ji, Jie Zhang, Hua Yang, Yalin Zhang, Kathi L. Heffner, Chun Wang, Ning Zhang   +8 more
doaj   +1 more source

A Theoretical Framework for Evaluating Psychiatric Research Strategies

Computational Psychiatry, 2017
One of the major goals of basic studies in psychiatry is to find etiological mechanisms or biomarkers of mental disorders. A standard research strategy to pursue this goal is to compare observations of potential factors from patients with those from ...
Kentaro Katahira, Yuichi Yamashita
doaj   +1 more source

A Research Domain Criteria Approach to Gambling Disorder and Behavioral Addictions: Decision-Making, Response Inhibition, and the Role of Cannabidiol

Frontiers in Psychiatry, 2021
Gambling Disorder (GD) has been recently re-classified in the DSM-5 under the “substance-related and addictive disorders,” in light of its genetic, endophenotypic, and phenotypic resemblances to substance dependence. Diminished control is a core defining
Stefano Pallanti, Stefano Pallanti, Anna Marras, Anna Marras, Nikolaos Makris   +4 more
doaj   +1 more source

Historical Underpinnings of Bipolar Disorder Diagnostic Criteria

Behavioral Sciences, 2016
Mood is the changing expression of emotion and can be described as a spectrum. The outermost ends of this spectrum highlight two states, the lowest low, melancholia, and the highest high, mania.
Brittany L. Mason, E. Sherwood Brown, Paul E. Croarkin   +2 more
doaj   +1 more source

The Research Domain Criteria: moving the goalposts to change the game [PDF]

British Journal of Psychiatry, 2014
SummaryThere is increasing concern that a reliance on the descriptive, syndrome-based diagnostic criteria of ICD and DSM is impeding progress in research. The USA's major funder of psychiatric research, the National Institute of Mental Health (NIMH), have stated their intention to ...
Joanne L, Doherty, Michael J, Owen
openaire   +2 more sources

Ontological representation–oriented term normalization and standardization of the Research Domain Criteria

Health Informatics Journal, 2020
The Research Domain Criteria, launched by the National Institute of Mental Health, is a new dimensional and interdisciplinary research framework for mental disorders. The Research Domain Criteria matrix is its core part.
Fang Li, Guozheng Rao, Jingcheng Du, Yang Xiang, Yaoyun Zhang, Salih Selek, Jane Elizabeth Hamilton, Hua Xu, Cui Tao   +8 more
doaj   +1 more source

Updating the research domain criteria: the utility of a motor dimension [PDF]

Psychological Medicine, 2015
Within the NIMH Research Domain Criteria (RDoC) framework, dimensions of behavior are investigated across diagnoses with the goal of developing a better understanding of their underlying neural substrates. Currently, this framework includes five domains: cognitive, social, arousal/regulatory, negative, and positive valence systems.
J A, Bernard, V A, Mittal
openaire   +2 more sources

Cultural adaptation of the facial emotion perception test for use in Zimbabwe: A pilot study

South African Journal of Psychiatry
Background: In African countries, including Zimbabwe, about half of those with depression respond to first-line therapies like problem-solving therapy. Predicting who needs more intensive treatment is challenging.
Denford Gudyanga, Primrose Nyamayaro, Summer Frandsen, Rebecca Easter, Sarah Derveeuw, Pauline Thibaut, Alina Dillahunt, Conall O’Cleirigh, Leah Rubin, Scott A. Langenecker, Melanie Abas   +10 more
doaj   +1 more source