Results 31 to 40 of about 2,205,527 (302)

A Research Domain Criteria (RDoC)-Guided Dashboard to Review Psilocybin Target Domains: A Systematic Review. [PDF]

CNS Drugs, 2022
Preliminary results from randomized controlled studies as well as identified molecular, cellular, and circuit targets of select psychedelics (e.g., psilocybin) suggest that their effects are transdiagnostic. In this review, we exploit the Research Domain
Pouyan N, Halvaei Khankahdani Z, Younesi Sisi F, Lee Y, Rosenblat JD, Teopiz KM, Lui LMW, Subramaniapillai M, Lin K, Nasri F, Rodrigues N, Gill H, Lipsitz O, Cao B, Ho R, Castle D, McIntyre RS.   +16 more
europepmc   +2 more sources

Motor actions across psychiatric disorders: A research domain criteria (RDoC) perspective. [PDF]

Clin Psychol Rev
The motor system is critical for understanding the pathophysiology and treatment of mental illness. Abnormalities in the processes that allow us to plan and execute movement in a goal-directed, context-appropriate manner (i.e., motor actions) are ...
Osborne KJ, Walther S, Mittal VA.
europepmc   +2 more sources

Mapping Research Domain Criteria using a transdiagnostic mini-RDoC assessment in mental disorders: a confirmatory factor analysis. [PDF]

Eur Arch Psychiatry Clin Neurosci, 2023
This study aimed to build on the relationship of well-established self-report and behavioral assessments to the latent constructs positive (PVS) and negative valence systems (NVS), cognitive systems (CS), and social processes (SP) of the Research Domain ...
Förstner BR, Tschorn M, Reinoso-Schiller N, Maričić LM, Röcher E, Kalman JL, Stroth S, Mayer AV, Schwarz K, Kaiser A, Pfennig A, Manook A, Ising M, Heinig I, Pittig A, Heinz A, Mathiak K, Schulze TG, Schneider F, Kamp-Becker I, Meyer-Lindenberg A, Padberg F, Banaschewski T, Bauer M, Rupprecht R, Wittchen HU, Rapp MA.   +26 more
europepmc   +2 more sources

Domain-driven multiple-criteria decision-making for flight crew decision support tool [PDF]

, 2023
During the flight, the crew might consider modifying their planned trajectory, taking into account currently available information, such as an updated weather forecast report or the already accrued amount of delay.
Delgado, L., Prats, X., Montlaur, A.
core   +1 more source

Evaluation of delay discounting as a transdiagnostic research domain criteria indicator in 1388 general community adults. [PDF]

Psychol Med, 2023
Background The Research Domain Criteria (RDoC) approach proposes a novel psychiatric nosology using transdiagnostic dimensional mechanistic constructs. One candidate RDoC indicator is delay discounting (DD), a behavioral economic measure of impulsivity ...
Levitt EE, Oshri A, Amlung M, Ray LA, Sanchez-Roige S, Palmer AA, MacKillop J.   +6 more
europepmc   +2 more sources

Research Domain Criteria in NIMH Grants Characterized Using Large Language Models.

JAMA Netw Open
This cohort study uses a large language model to examine changes in research funding from the National Institute of Mental Health (NIMH) for Research Domain Criteria domains and transdiagnostic investigation.
Perlis RH.
europepmc   +2 more sources

The multimodal Munich Clinical Deep Phenotyping study to bridge the translational gap in severe mental illness treatment research

Frontiers in Psychiatry, 2023
IntroductionTreatment of severe mental illness (SMI) symptoms, especially negative symptoms and cognitive dysfunction in schizophrenia, remains a major unmet need. There is good evidence that SMIs have a strong genetic background and are characterized by
Lenka Krčmář, Lenka Krčmář, Iris Jäger, Emanuel Boudriot, Katharina Hanken, Vanessa Gabriel, Julian Melcher, Nicole Klimas, Fanny Dengl, Susanne Schmoelz, Pauline Pingen, Mattia Campana, Joanna Moussiopoulou, Vladislav Yakimov, Georgios Ioannou, Sven Wichert, Silvia DeJonge, Peter Zill, Boris Papazov, Valéria de Almeida, Sabrina Galinski, Nadja Gabellini, Genc Hasanaj, Matin Mortazavi, Temmuz Karali, Alexandra Hisch, Marcel S Kallweit, Verena J. Meisinger, Lisa Löhrs, Karin Neumeier, Stephanie Behrens, Susanne Karch, Benedikt Schworm, Christoph Kern, Siegfried Priglinger, Berend Malchow, Johann Steiner, Johann Steiner, Johann Steiner, Johann Steiner, Alkomiet Hasan, Frank Padberg, Oliver Pogarell, Peter Falkai, Peter Falkai, Andrea Schmitt, Andrea Schmitt, Elias Wagner, Daniel Keeser, Daniel Keeser, Daniel Keeser, Florian J. Raabe, Florian J. Raabe, Florian J. Raabe   +53 more
doaj   +1 more source

Precision psychiatry and Research Domain Criteria: Implications for clinical trials and future practice

CNS Spectrums, 2023
Psychiatric disorders are associated with significant social and economic burdens, many of which are related to issues with current diagnosis and treatments.
Leanne M. Williams, William T. Carpenter, Carrie Carretta, E. Papanastasiou, Uma Vaidyanathan   +4 more
semanticscholar   +1 more source

Neuroimaging findings of adolescent depression: A review by the Research Domain Criteria (RDoC) framework. [PDF]

Psychiatry Res Neuroimaging
This review examines neuroimaging studies on adolescent depression (AD) within the Research Domain Criteria (RDoC) framework, focusing on fMRI, DTI, and EEG findings.
Jeong H, Luo T, Kang M, Garvey WF, Blankenau G, Suk JW, Tarzaben M, Hwang S.   +7 more
europepmc   +2 more sources

Using Development and Psychopathology Principles to Inform the Research Domain Criteria (RDoC) Framework. [PDF]

Dev Psychopathol, 2021
In 2010, the Research Domain Criteria (RDoC) were developed to advance our understanding of the pathophysiology of mental illness across multiple levels of analysis, ranging from cells to circuits to self-report instruments.
Conradt E, Crowell SE, Cicchetti D.
europepmc   +2 more sources