Results 51 to 60 of about 69,132,749 (274)

Potential Cross Talk between Autism Risk Genes and Neurovascular Molecules: A Pilot Study on Impact of Blood Brain Barrier Integrity

open access: yesCells, 2022
Autism Spectrum Disorder (ASD) is a common pediatric neurobiological disorder with up to 80% of genetic etiologies. Systems biology approaches may make it possible to test novel therapeutic strategies targeting molecular pathways to alleviate ASD ...
Rekha Jagadapillai   +7 more
doaj   +1 more source

Attribution Retraining Group Therapy and SSRIs Affect Differing Facets of Anxiety Among Chinese Patients with Various Diagnoses: A Single-Center, Prospective Study

open access: yesPsychiatry and Clinical Psychopharmacology, 2021
Background: The NIMH launched a Research Domain Criteria (RDoC) initiative, which encouraged researchers to shift from traditional categorical conceptions of mental disorders to process-oriented psychological functions described by constructs.
Jingya Kong   +8 more
doaj   +1 more source

O projeto Research Domain Criteria e o abandono da tradição psicopatológica

open access: yesRevista Latinoamericana de Psicopatologia Fundamental, 2014
O artigo explora os pressupostos epistemológicos do Research Domain Criteria (RDoC) - projeto de investigação empírica dos transtornos mentais, dentro de uma plataforma biológica - promovido pelo National Institute of Mental Health (NIMH).
Rafaela Zorzanelli   +2 more
doaj   +1 more source

Effects of stress on endophenotypes of suicide across species: A role for ketamine in risk mitigation

open access: yesNeurobiology of Stress, 2022
Suicide is a leading cause of death and morbidity worldwide, yet few interventions are available to mitigate its risk. Barriers to effective treatments involve a limited understanding of factors that predict the onset of suicidal thoughts and behaviors ...
Steven J. Lamontagne   +2 more
doaj   +1 more source

A Theoretical Framework for Evaluating Psychiatric Research Strategies

open access: yesComputational Psychiatry, 2017
One of the major goals of basic studies in psychiatry is to find etiological mechanisms or biomarkers of mental disorders. A standard research strategy to pursue this goal is to compare observations of potential factors from patients with those from ...
Kentaro Katahira, Yuichi Yamashita
doaj   +1 more source

A Research Domain Criteria Approach to Gambling Disorder and Behavioral Addictions: Decision-Making, Response Inhibition, and the Role of Cannabidiol

open access: yesFrontiers in Psychiatry, 2021
Gambling Disorder (GD) has been recently re-classified in the DSM-5 under the “substance-related and addictive disorders,” in light of its genetic, endophenotypic, and phenotypic resemblances to substance dependence. Diminished control is a core defining
Stefano Pallanti   +4 more
doaj   +1 more source

The Research Domain Criteria: moving the goalposts to change the game [PDF]

open access: yesBritish Journal of Psychiatry, 2014
SummaryThere is increasing concern that a reliance on the descriptive, syndrome-based diagnostic criteria of ICD and DSM is impeding progress in research. The USA's major funder of psychiatric research, the National Institute of Mental Health (NIMH), have stated their intention to ...
Joanne L, Doherty, Michael J, Owen
openaire   +2 more sources

Historical Underpinnings of Bipolar Disorder Diagnostic Criteria

open access: yesBehavioral Sciences, 2016
Mood is the changing expression of emotion and can be described as a spectrum. The outermost ends of this spectrum highlight two states, the lowest low, melancholia, and the highest high, mania.
Brittany L. Mason   +2 more
doaj   +1 more source

The Atlas of Australia Online 2023 [PDF]

open access: yes, 2023
The Atlas of Australia Online 2023 research report provides a contemporary atlas of the Australian internet, and reveals important insights into the digital landscape of Australia. It does so by augmenting the .au Domain Administration (auDA) domain name
Gong, X   +3 more
core   +1 more source

Updating the research domain criteria: the utility of a motor dimension [PDF]

open access: yesPsychological Medicine, 2015
Within the NIMH Research Domain Criteria (RDoC) framework, dimensions of behavior are investigated across diagnoses with the goal of developing a better understanding of their underlying neural substrates. Currently, this framework includes five domains: cognitive, social, arousal/regulatory, negative, and positive valence systems.
J A, Bernard, V A, Mittal
openaire   +2 more sources

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