Results 91 to 100 of about 10,894,164 (293)
Quality‐assured research environments for translational cancer research [PDF]
Molecular Oncology, 2019 In order to secure high‐quality cancer care for increasing numbers of cancer patients in the upcoming decades, the complete continuum of cancer research and cancer care needs a thorough overhaul, with more emphasis on prevention and early detection, and a greater focus on the development of innovative treatments that are also scrutinised for ...
openaire +3 more sources
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
FEBS Letters, EarlyView.Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
FEBS Letters, EarlyView.Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas +3 more
wiley +1 more source
Virtual Research Environments: An Overview and a Research Agenda
Data Science Journal, 2013 Virtual Research Environments are innovative, web-based, community-oriented, comprehensive, flexible, and secure working environments conceived to serve the needs of modern science. We overview the existing initiatives developing these environments by highlighting the major distinguishing features.
Candela L, Castelli D, Pagano P
openaire +4 more sources
The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes
FEBS Letters, EarlyView.Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga +3 more
wiley +1 more source
A Bibliometric Analysis of the Outdoor Thermal Environment Based on CiteSpace
BuildingsThe outdoor thermal environment (OTE) is closely related to sustainable urban development and human living, and related research has attracted widespread attention.
Chao Xie, Tangjun Feng, Li Hu
doaj +1 more source
FEBS Letters, EarlyView.Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source
Personalização: um serviço mediador em ambientes de pesquisa
TransinformaçãoA grande quantidade de informações no ambiente digital dificulta a sua organização e recuperação. Recursos de personalização podem direcionar e recomendar informações mais específicas para determinado tipo de usuário.
Liriane Soares de Araújo de Camargo +1 more
doaj
Accounting and Environment: An Analysis of Academic Literature in Journals
Revista Sociedade, Contabilidade e Gestão, 2014 Since ancient times economic activity has brought environmental impacts. However, in recent years the society has been showing an increasing concern with environmental issues.
José Ricardo Maia de Siqueira
doaj
Agroforestry: Reconciling Production with Protection of the Environment A Synopsis of Research Literature [PDF]
, 2010 This is a synopsis of research literature that investigates the potential of temperate agroforestry as a sustainable production system. Agroforestry is a concept of integrated land use that combines elements of agriculture and forestry.
Smith, Jo
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