Results 61 to 70 of about 10,894,164 (293)
FEBS Letters, EarlyView.Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source
Research integrity: environment, experience, or ethos?
Research Ethics Review, 2019 Background: Research integrity has gained attention in the general public as well as in the research community. We wanted to investigate knowledge, attitudes, and practices amongst researchers that have recently finished their PhD and compare this to ...
Bjørn Hofmann, Søren Holm
doaj +1 more source
GATE -- an Environment to Support Research and Development in Natural Language Engineering [PDF]
, 1996 We describe a software environment to support research and development in natural language (NL) engineering. This environment -- GATE (General Architecture for Text Engineering) -- aims to advance research in the area of machine processing of natural ...
Cunningham, Hamish +4 more
core +4 more sources
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Perceptions of the Maltese public towards local Marine Protected Areas [PDF]
, 2015 The marine environment represents a central component of Malta's local environment, and its ecosystem services play a vital role in supporting the economy as well as human well-being.
Mifsud, Mark C., Verret, Marielle
core +1 more source
FEBS Letters, EarlyView.This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
The Royal Marsden BRIDgE TRE Transparency Project
International Journal of Population Data ScienceBackground The BRIDgE platform is the Royal Marsden’s Trusted Research environment, which aims to transform clinical practice and improve outcomes for patients by enabling data analytics and AI development using real-world cancer data within secure ...
Lisa Scerri, Naimh Adams
doaj +1 more source
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
FEBS Letters, EarlyView.We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
The Journal of Academic Librarianship, 2010 The article reviews the book "Virtual Research Environments: From Portals to Science Gateways," by Robert Allan.
openaire +3 more sources
Enabling AI Research within a Trusted Research Environment
International Journal of Population Data ScienceWe aimed to develop an AI governance framework for Trusted Research Environments (TREs) to assess the risks associated with releasing AI models trained on secure data.
Lewis Hotchkiss +2 more
doaj +1 more source